A synthesis of 5-hetaryl-3-(2-hydroxybenzoyl)pyrroles

被引：32

作者：

Plaskon, Andrey S. ^{[1
,2
]}

Ryabukhin, Sergey V. ^{[1
,2
]}

Volochnyuk, Dmitriy M. ^{[1
,3
]}

Shivanyuk, Alexander N. ^{[1
,2
]}

Tolmachev, Andrey A. ^{[2
]}

机构：

[1] Enamine Ltd, UA-01103 Kiev, Ukraine

[2] Natl Taras Shevchenko Univ, UA-01033 Kiev, Ukraine

[3] Natl Acad Sci Ukraine, Inst Organ Chem, UA-02094 Kiev, Ukraine

来源：

TETRAHEDRON | 2008年 / 64卷 / 25期

关键词：

3-formylchromone; pyrroles; hetarylmethylamines; recyclization; chlorotrimethylsilane;

D O I：

10.1016/j.tet.2008.04.041

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile and versatile procedure for the synthesis of 5-hetaryl-3-(2-hydroxybenzoyl)-1H-pyrroles and 4-(2-hydroxybenzoyl)-1H-pyrrole-2-carboxylic acid derivatives was established on the basis of TMSCl promoted recyclization of 3-formylchromone with various hetarylmethylamines and glycine derivatives. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：5933 / 5943

页数：11

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