Antisynthetase syndrome associated with sarcoidosis

被引：13

作者：

Asanuma, Yu ^{[1
]}

Koichihara, Reiko ^{[1
]}

Koyama, Shinichiro ^{[1
]}

Kawabata, Yoshinori ^{[2
]}

Kobayashi, Shio

Mimori, Tsuneyo ^{[3
]}

Moriguchi, Masato ^{[1
]}

机构：

[1] Jichi Med Sch, Omiya Med Ctr, Clin Dept Internal Med, Saitama, Japan

[2] Saitama Prefecture Cardiovasc & Resp Ctr, Dept Pathol, Saitama, Japan

[3] Kyoto Univ, Grad Sch Med, Dept Rheumatol & Clin Immunol, Kyoto, Japan

来源：

INTERNAL MEDICINE | 2006年 / 45卷 / 18期

关键词：

sarcoidosis; antisynthetase syndrome; interstitial pneumonia;

D O I：

10.2169/internalmedicine.45.1772

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 30-year-old man complained of polyarthralgia and fatigue. The clinical findings and laboratory data included myositis, polyarthritis, interstitial pneumonia, Raynaud's phenomenon, mechanic's hand, and anti PL-7 antibody (threonyl-tRNA synthetase antibody). All of these signs were consistent with antisynthetase syndrome. His chest radiograph revealed bilateral hilar lymphadenopathy. Biopsy specimens from his mediastinal lymph node and muscle showed noncaseating epithelioid cell granulomas. Lung histology revealed nonspecific interstitial pneumonia. Antisynthetase syndrome associated with sarcoidosis was diagnosed. Interstitial pneumonia in this patient responded well to high-dose corticosteroid therapy.

引用

页码：1065 / 1068

页数：4

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