The role of the Patient-Generated Subjective Global Assessment (PG-SGA) and biochemical markers in predicting anemia patients with cancer

被引：8

作者：

Wu, Meng ^{[1
]}

Lian, Xiao-Jiao ^{[1
]}

Jia, Jun-Mei ^{[2
]}

Cao, Wen-Ting ^{[3
]}

Yan, Na ^{[3
]}

Xin, Yan-Mei ^{[3
]}

Liu, Zeng-Rong ^{[3
]}

Li, Hua-Yan ^{[3
]}

Fan, Zhi-Fang ^{[3
]}

Sun, Ping ^{[3
]}

机构：

[1] Shanxi Med Univ, Sch Publ Hlth, Dept Nutr & Food Hyg, 56 Xinjiannanlu St, Taiyuan 030001, Shanxi, Peoples R China

[2] Shanxi Med Univ, Clin Med Sch 1, Dept Oncol, 85 Jiefangnanlu St, Taiyuan 030001, Shanxi, Peoples R China

[3] Shanxi Med Univ, Clin Med Sch 1, Dept Nutr, 85 Jiefangnanlu St, Taiyuan 030001, Shanxi, Peoples R China

来源：

SUPPORTIVE CARE IN CANCER | 2019年 / 27卷 / 04期

关键词：

Anemia; Malnutrition; Nutritional assessment; Patient-generated subjective global assessment; QUALITY-OF-LIFE; NUTRITIONAL-STATUS; GYNECOLOGIC CANCER; MALNUTRITION; PREVALENCE; INFLAMMATION; SUPPORT;

D O I：

10.1007/s00520-018-4462-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

PurposeThe causes of anemia and the common side effects of cancer are multifactorial. Malnutrition is one of the alleged components of the aforementioned complications. This study planned to investigate the relationship among biochemical markers, Patient-Generated Subjective Global Assessment (PG-SGA), and anemia in cancer patients.MethodsThis analysis consisted of 234 patients who were enlisted in the Department of Oncology of the First Hospital of Shanxi Medical University between December 2016 and October 2017. The groups were divided into anemic and non-anemic patients. The gathered data primarily discussed the patients' basic information, specifically the age, gender, smoking, alcohol consumption, and nutritional status based on levels of serum biochemical markers and PG-SGA scores.ResultsAmong the participants, 31.2% of the cancer patients were diagnosed with anemia whereas, according to the scores of PG.SGA, 65.0% of patients experienced malnourishment. The anemia was significantly associated with biochemical markers, expecting a transferrin in univariable analyses. Binary logistic regression analysis between anemic cancer patients and non-anemic cancer patients suggested that high PG-SGA score (odds ratio 1.082; 95% CI 1.027-1.141) implied the risk factor for anemia, and high PG-SGA scores could potentially increase the risk of anemia. The multiple regression analysis showed that hemoglobin concentration (OR 0.575; 95% CI 0.450-0.736) and PG-SGA score (OR 1.231; 95% CI 1.013-1.496) were linked to anemia. However, total protein, albumin, prealbumin, serum iron, transferrin, and transferrin saturation lacked a strong relationship with anemia.ConclusionAnemia prevailed in cancer patients, as nutritionally assessed by PG-SGA, while hemoglobin established a linkage with anemia as they could provide extra predictive information about anemia in patients diagnosed with cancer.

引用

页码：1443 / 1448

页数：6