Total pancreatectomy with islet autotransplantation: an overview

被引：37

作者：

Ong, Seok L. ^{[1
]}

Gravante, Gianpiero ^{[1
]}

Pollard, Cristina A. ^{[1
]}

Webb, M'Balu A. ^{[1
]}

Illouz, Severine ^{[1
]}

Dennison, Ashley R. ^{[1
]}

机构：

[1] Leicester Gen Hosp, Dept Hepatobiliary & Pancreat Surg, Leicester LE5 4PW, Leics, England

来源：

HPB | 2009年 / 11卷 / 08期

关键词：

total pancreatectomy; islet; autotransplantation;

D O I：

10.1111/j.1477-2574.2009.00113.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Pain control is one of the most challenging aspects in the management of chronic pancreatitis. Total pancreatectomy can successfully relieve the intractable abdominal pain in these patients but will inevitably result in insulin-dependent diabetes. Islet autotransplantation aims to preserve, as far as possible, the insulin secretory function of the islet cell mass thereby reducing (or even removing) the requirement for exogenous insulin administration after a total pancreactomy. Despite the relatively small number of centres able to perform these procedures, there are important technical variations in the details of their approaches. The aim of this review is to provide details of the current surgical practice for total pancreatectomy combined with islet autotransplantation, and outline the potential advantages and disadvantages of the variations adopted in each centre.

引用

页码：613 / 621

页数：9

共 49 条

[1] Factors associated with insulin and narcotic independence after islet autotransplantation in patients with severe chronic pancreatitis [J].

Ahmad, SA ;

Lowy, AM ;

Wray, CJ ;

D'Alessio, D ;

Choe, KA ;

James, LE ;

Gelrud, A ;

Matthews, JB ;

Rilo, HLR .

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2005, 201 (05) :680-687

[2] Mechanisms and emerging treatments of the metabolic complications of chronic pancreatitis [J].

Andersen, Dana K. .

PANCREAS, 2007, 35 (01) :1-15

[3]

Argo JL, 2008, AM SURGEON, V74, P530

[4] Early Metabolic Markers of Islet Allograft Dysfunction [J].

Baidal, David A. ;

Faradji, Raquel N. ;

Messinger, Shari ;

Froud, Tatiana ;

Monroy, Kathy ;

Ricordi, Camillo ;

Alejandro, Rodolfo .

TRANSPLANTATION, 2009, 87 (05) :689-697

[5] The role of total pancreatectomy and islet auto transplantation for chronic pancreatitis [J].

Blondet, Juan J. ;

Carlson, Annelisa M. ;

Kobayashi, Takashi ;

Jie, Tun ;

Bellin, Melena ;

Hering, Bernhard J. ;

Freeman, Martin L. ;

Beilman, Greg J. ;

Sutherland, David E. R. .

SURGICAL CLINICS OF NORTH AMERICA, 2007, 87 (06) :1477-+

[6] Pathogenesis of pain in chronic pancreatitis:: Ongoing enigma [J].

Bornman, PC ;

Marks, IN ;

Girdwood, AW ;

Berberat, PO ;

Gulbinas, A ;

Büchler, MW .

WORLD JOURNAL OF SURGERY, 2003, 27 (11) :1175-1182

[7] Portal venous pressure changes after sequential clinical islet transplantation [J].

Casey, JJ ;

Lakey, JRT ;

Ryan, EA ;

Paty, BW ;

Owen, R ;

O'Kelly, K ;

Nanji, S ;

Rajotte, RV ;

Korbutt, GS ;

Bigam, D ;

Kneteman, NN ;

Shapiro, AMJ .

TRANSPLANTATION, 2002, 74 (07) :913-915

[8]

*CITR, 2008 COLL ISL TRANSP

[9] Pancreatectomy with islet autotransplantation for the treatment of severe chronic pancreatitis: The first 40 patients at the Leicester General Hospital [J].

Clayton, HA ;

Davies, JE ;

Pollard, CA ;

White, SA ;

Musto, PP ;

Dennison, AR .

TRANSPLANTATION, 2003, 76 (01) :92-98

[10]

FARNEY AC, 1991, SURGERY, V110, P427

← 1 2 3 4 5 →