The Failure of Immunosuppression Withdrawal: Patient Benefit Is Not Detectable, Inducible, or Reproducible

被引：9
作者：
Porrett, Paige [1 ]
Shaked, Abraham [1 ]
机构：
[1] Univ Penn, Dept Surg, Philadelphia, PA 19104 USA
来源：
LIVER TRANSPLANTATION | 2011年 / 17卷
关键词：
LIVER-TRANSPLANT RECIPIENTS; FOLLOW-UP; MINIMIZATION; TOLERANCE; TRIAL;
D O I：
10.1002/lt.22377
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Key Points (1) Immunosuppression is responsible for excellent patient outcomes. (2) Immunosuppression withdrawal fails in most patients. (3) Patients who may benefit from immunosuppression withdrawal cannot currently be identified. (4) No data suggest that immunosuppression withdrawal decreases patient morbidity (ie, nephrotoxicity). (5) The minimization of immunosuppression instead of withdrawal may be adequate for improving patient outcomes. Liver Transpl 17:S66-S68, 2011. (C) 2011 AASLD.
引用
收藏
页码：S66 / S68
页数：3
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