Hydrogel stamping of arrays of supported lipid bilayers with various lipid compositions for the screening of drug-membrane and protein-membrane interactions

被引：64
|
作者：
Majd, S
Mayer, M
机构：
[1] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Chem Engn, Ann Arbor, MI 48109 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 41期
关键词：
hydrogel; lipids; membranes; micropatterning;
D O I：
10.1002/anie.200502189
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Stamping on fat: Agarose gel stamps were used to create ≥100 membrane arrays (see picture) by using only picomolar amounts of lipids. This constitutes a rapid and straightforward method for the fabrication of functional membrane arrays with a variety of lipid compositions which can be used for screening assays, for example, for drug-membrane interactions. (Figure Presented) © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：6697 / 6700
页数：4
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