Treatment of malignant gastroduodenal obstruction with a nitinol self-expanding metal stent: An international prospective multicentre registry

被引：54

作者：

Costamagna, Guido ^{[1
]}

Tringali, Andrea ^{[1
]}

Spicak, Julius ^{[2
]}

Mutignani, Massimiliano ^{[1
]}

Shaw, John ^{[3
]}

Roy, Andre ^{[4
]}

Johnsson, Erik ^{[5
]}

De Moura, Eduardo G. H. ^{[6
]}

Cheng, Spencer ^{[6
]}

Ponchon, Thierry ^{[7
]}

Bittinger, Max ^{[8
]}

Messmann, Helmut ^{[8
]}

Neuhaus, Horst ^{[9
]}

Schumacher, Brigitte ^{[9
]}

Laugier, Rene ^{[10
]}

Saarnio, Juha ^{[11
]}

Igea Ariqueta, Francisco ^{[12
]}

机构：

[1] Policlin A Gemelli, Rome, Italy

[2] IKEM, Prague, Czech Republic

[3] Groote Schuur Hosp, ZA-7925 Cape Town, South Africa

[4] CHUM, Montreal, PQ, Canada

[5] Gothenburg Univ, Sahlgrens Hosp, S-41345 Gothenburg, Sweden

[6] Univ Sao Paulo, Fac Med, Hosp Clin, BR-05508 Sao Paulo, Brazil

[7] Edouard Herriot, Lyon, France

[8] Klinikum Augsburg, Med Klin 3, Augsburg, Germany

[9] Evangel Krankenhaus Duesseldorf, Dusseldorf, Germany

[10] Hop Enfants La Timone, Marseille, France

[11] Oulu Univ Hosp, Oulu, Finland

[12] Hosp Rio Carrion, Palencia, Spain

来源：

DIGESTIVE AND LIVER DISEASE | 2012年 / 44卷 / 01期

关键词：

Duodenal stem; Endoscopic stenting; Gastric Outlet Obstruction Score; Malignant gastric and duodenal stricture; GASTRIC OUTLET OBSTRUCTION; ENDOSCOPIC PALLIATION; SURGICAL BYPASS; ENTERAL STENTS; GASTROJEJUNOSTOMY; TRIAL;

D O I：

10.1016/j.dld.2011.08.012

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: Duodenal stenting has become a broadly accepted first line of treatment for patients with advanced malignant gastroduodenal obstruction as these patients are difficult to treat and are poor surgical candidates. Aims: To document duodenal stent performance for palliative management of malignant gastroduodenal obstruction. Methods: Multicentre, single arm, prospective registry documenting peroral endoscopic duodenal stenting procedures in 202 patients. Results: Technical success achieved in 98% (CI. 95%, 99%) of stent placements. Increase of Gastric Outlet Obstruction Score by at least 1 point compared to baseline was achieved in 91% (CI, 86%, 95%) of patients persisting for a median of 184 days (CI, 109, 266). By day 5 (CI, 4,6) after stent placement, 50% of patients experienced a score increase of at least 1 point. Improvement from 14% of patients at baseline tolerating soft solids or low residue/normal diet to 84% at 15 days, 86% at 30 days, 81% at 90 days, 79% at 180 days, and 70% at 270 days. Complications included stent ingrowth and/or overgrowth (12.4%), transient periprocedural symptoms (3%), bleeding (3%), stent migration (1.5%), and perforation (0.5%). Conclusions: Safety and effectiveness of duodenal stenting for palliation of malignant gastroduodenal obstruction was confirmed in the largest international prospective series to date. (C) 2011 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

引用

页码：37 / 43

页数：7

共 21 条

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