The C-reactive protein to albumin ratio predicts postoperative complication in patients who undergo gastrectomy for gastric cancer

被引：9
作者：
Lee, Jin Won [1 ,2 ]
Sharma, Ashish Ranjan [3 ]
Lee, Sang-Soo [3 ]
Chun, Wan Joo [2 ]
Kim, Hae Sung [1 ]
机构：
[1] Hallym Univ, Chuncheon Sacred Heart Hosp, Dept Surg, Coll Med, Chunchon, South Korea
[2] Kangwon Natl Univ, Dept Pharmacol, Coll Med, Chunchon, South Korea
[3] Hallym Univ, Chuncheon Sacred Heart Hosp, Inst Skeletal Aging & Orthoped Surg, Chunchon 24252, Gangwon Do, South Korea
来源：
HELIYON | 2020年 / 6卷 / 06期
关键词：
Gastrointestinal system; Pathology; Surgery; Immunology; Oncology; Clinical research; C-reactive protein to albumin ratio; Gastric cancer; Postoperative complication; INFECTIOUS COMPLICATIONS; CURATIVE RESECTION; SURGERY; RISK; MORBIDITY; PROGNOSIS; SEVERITY;
D O I：
10.1016/j.heliyon.2020.e04220
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The aim of this study was to evaluate the preoperative C-reactive protein (CRP) to albumin ratio (CAR) of patients with gastric cancer and to investigate the factors correlated with perioperative complications. From March 2016 to December 2019, 128 patients who underwent curative gastrectomy for gastric cancer were enrolled in a retrospective study. The preoperative cutoff value of the CAR for predicting postoperative complications was 0.265 on receiver operating characteristic (ROC) curve analysis. Clinical characteristics were compared between patients with complications (Clavien-Dindo grade 2, n = 20) and without complications (Clavien-Dindo grade <2, n = 108). On univariate and multivariate analyses, estimated blood loss (EBL) during the operation (HR 1.003, p = 0.039) and CAR (HR 2.832, p = 0.045) were independent predictors of postoperative complications. In conclusion, preoperative CAR appears to be a predictor of postoperative complications in the patients undergoing surgical treatment of gastric cancer.
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页数：5
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