Aggressive B cell lymphomas in the 2017 revised WHO classification of tumors of hematopoietic and lymphoid tissues

被引：78

作者：

Grimm, Kate E. ^{[1
]}

O'Malley, Dennis P. ^{[2
,3
]}

机构：

[1] OMalley Med Consulting Inc, Charlotte, NC USA

[2] Neogenomics, Aliso Viejo, CA 92656 USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA

来源：

ANNALS OF DIAGNOSTIC PATHOLOGY | 2019年 / 38卷

关键词：

Large B cell lymphoma; Aggressive lymphoma; Molecular classification of DLBCL; DLBCL; DLBCL subtypes; WHO classification; HODGKIN LYMPHOMA; IDENTIFY; SUBTYPE;

D O I：

10.1016/j.anndiagpath.2018.09.014

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The recent 2017 update of the World Health Organization classification of lymphomas has significant changes from the previous edition. Subtypes of large B cell lymphoma and related aggressive B cell lymphomas are addressed. Clinicopathological features of entities as related to morphology, immunophenotype, cell of origin, and molecular/genetic findings are reviewed with emphasis on changes or updates in findings. Specific subtypes addressed include: T cell/histiocyte-rich large B cell lymphoma, primary diffuse large B cell lymphoma (DLBCL) of the CNS, primary cutaneous DLBCL leg-type, EBV-positive DLBCL, NOS, DLBCL associated with chronic inflammation, primary mediastinal large B cell lymphoma, intravascular large B cell lymphoma, ALE-positive large B cell lymphoma, plasmablastic lymphoma, primary effusion lymphoma, HHV8-positive diffuse large B-cell lymphoma, NOS, Burkitt lymphoma, Burkitt-like lymphoma with 11q aberration, high-grade B cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements, high grade B cell lymphoma, NOS, B cell lymphoma, unclassifiable, with features intermediate between DLBCL and classic Hodgkin lymphoma and large B cell lymphoma with IRF4 translocation. In addition, EBV positive mucocutaneous ulcer is addressed.

引用

页码：6 / 10

页数：5

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