Rh-catalyzed asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution

被引：6

作者：

Fan, Dongyang ^{[1
]}

Lu, Jian ^{[2
]}

Liu, Yang ^{[1
]}

Zhang, Zhenfeng ^{[1
]}

Liu, Yangang ^{[1
]}

Zhang, Wanbin ^{[1
,2
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Pharm, 800 Dongchuan Rd, Shanghai 200240, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, 800 Dongchuan Rd, Shanghai 200240, Peoples R China

来源：

TETRAHEDRON | 2016年 / 72卷 / 35期

基金：

中国国家自然科学基金;

关键词：

Asymmetric hydrogenation; Dynamic kinetic resolution; Chiral arylglycines; Racemic aldimines; Rhodium complex; ALPHA-IMINO ESTERS; N-H INSERTION; ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; NK1 RECEPTOR ANTAGONIST; AMINO-ACID-ESTERS; ENANTIOSELECTIVE HYDROGENATION; STEREOSELECTIVE HYDROGENATION; REDUCTIVE AMINATION; ROOM-TEMPERATURE; DIAZO-COMPOUNDS;

D O I：

10.1016/j.tet.2016.07.046

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalyzed by a rhodium complex of P-stereogenic diphosphine ligand trichickenfootphos (TCFP), asymmetric hydrogenation of racemic aldimines via dynamic kinetic resolution has been realized for the preparation of chiral arylglycines with good yields and enantioselectivities. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：5541 / 5547

页数：7

共 75 条

[71] Rh-Catalyzed Asymmetric Hydrogenation of Cyclic α-Dehydroamino Ketones [J].

Zhang, Zhenfeng ;

Hu, Qiupeng ;

Wang, Yingjie ;

Chen, Jianzhong ;

Zhang, Wanbin .

ORGANIC LETTERS, 2015, 17 (21) :5380-5383

[72] Enantioselective Synthesis of Chiral β-Aryloxy Alcohols by Asymmetric Hydrogenation of α-Aryloxy Aldehydes via Dynamic Kinetic Resolution [J].

Zhou, Zhang-Tao ;

Xie, Jian-Hua ;

Zhou, Qi-Lin .

ADVANCED SYNTHESIS & CATALYSIS, 2009, 351 (03) :363-366

[73] Enantioselective Organocatalytic Transfer Hydrogenation of α-Imino Esters by Utilization of Benzothiazoline as Highly Efficient Reducing Agent [J].

Zhu, Chen ;

Akiyama, Takahiko .

ADVANCED SYNTHESIS & CATALYSIS, 2010, 352 (11-12) :1846-1850

[74] Well-Defined Binuclear Chiral Spiro Copper Catalysts for Enantioselective N-H Insertion [J].

Zhu, Shou-Fei ;

Xu, Bin ;

Wang, Guo-Peng ;

Zhou, Qi-Lin .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (01) :436-442

[75] One-pot efficient synthesis of aryl α-keto esters from aryl-ketones [J].

Zhuang, Jing ;

Wang, Changqing ;

Xie, Fang ;

Zhang, Wanbin .

TETRAHEDRON, 2009, 65 (47) :9797-9800

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