Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields

被引：83

作者：

Varma, V. B. ^{[1
]}

Ray, A. ^{[1
]}

Wang, Z. M. ^{[1
]}

Wang, Z. P. ^{[2
]}

Ramanujan, R. V. ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore

[2] Singapore Inst Mfg Technol, 71 Nanyang Dr, Singapore 638075, Singapore

来源：

SCIENTIFIC REPORTS | 2016年 / 6卷

关键词：

FLOW-FOCUSING DEVICE; FERROFLUID DROPLETS; BREAKUP DYNAMICS; DRUG DISCOVERY; MICROFLUIDICS; MICROPARTICLES; DEFORMATION; TRANSCRIPTOMICS; COALESCENCE; TECHNOLOGY;

D O I：

10.1038/srep37671

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Droplet microfluidics offers a range of Lab-on-a-chip (LoC) applications. However, wireless and programmable manipulation of such droplets is a challenge. We address this challenge by experimental and modelling studies of uniform magnetic field induced merging of ferrofluid based droplets. Control of droplet velocity and merging was achieved through uniform magnetic field and flow rate ratio. Conditions for droplet merging with respect to droplet velocity were studied. Merging and mixing of colour dye + magnetite composite droplets was demonstrated. Our experimental and numerical results are in good agreement. These studies are useful for wireless and programmable droplet merging as well as mixing relevant to biosensing, bioassay, microfluidic-based synthesis, reaction kinetics, and magnetochemistry.

引用

页数：12

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