Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields

被引:39
|
作者
Scarfi, MR
Lioi, MB
Zeni, O
Della Noce, M
Franceschi, C
Bersani, F
机构
[1] CNR, IRECE, Interuniv Ctr Electromagnet Fields & Biosyst, I-80124 Naples, Italy
[2] Univ Basilicata, Dept Anim Sci, I-85100 Potenza, Italy
[3] Univ Modena, Dept Biomed Sci, I-41100 Modena, Italy
[4] Univ Bologna, Dept Phys, I-40126 Bologna, Italy
来源
HEALTH PHYSICS | 1999年 / 76卷 / 03期
关键词
magnetic fields; bioassay; tumors; radiation; nonionizing;
D O I
10.1097/00004032-199903000-00005
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
In the present study micronucleus induction and cell proliferation in human peripheral blood lymphocytes cultured in vitro and exposed to 50 Hz sinusoidal magnetic fields for 72 h at different intensities (1.0, 0.75, 0.5, 0.25, and 0.05 mT rms) were investigated. The results obtained from 42 healthy donors aged between 26 and 54 y indicate that, for the field intensities tested, no genotoxic effects were found, as assessed by the cytokinesis-block micronucleus assay. On the contrary, cell proliferation, evaluated by the cytokinesis-block proliferation index, was slightly affected by the field at the intensities tested.
引用
收藏
页码:244 / 250
页数:7
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