A novel cascade reaction of aryl aldoxime with dimedone under microwave irradiation:: The synthesis of N-hydroxylacridine

被引：96

作者：

Tu, SJ ^{[1
]}

Gao, Y

Fang, F

Zhuang, QY

Feng, YJ

Shi, DQ

机构：

[1] Xuzhou Normal Univ, Key Lab Biotechnol Med Plant, Dept Chem, Xuzhou 221009, Jiangsu, Peoples R China

[2] Shenzhen Univ, Dept Chem, Shenzhen 518060, Guangdong, Peoples R China

来源：

SYNLETT | 2004年 / 02期

关键词：

aryl aldoxime; dimedone; N-hydroxylacridine; micro-wave;

D O I：

10.1055/s-2003-44981

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel sequential addition, elimination and cyclization reactions took place when aldoxime and dimedone in glycol was subjected to microwave irradiation and a new type of N-hydroxylacridinedione derivatives was obtained in excellent yields (80-95%) within a short reaction time (4-8 min).

引用

页码：255 / 258

页数：4

共 29 条

[1]

Abele E, 2000, HETEROCYCLES, V53, P2285

[2] 1,4-DIHYDROPYRIDINES - A BASIS FOR DEVELOPING NEW DRUGS [J].