Selected nanotechnologies and nanostructures for drug delivery, nanomedicine and cure

被引:46
作者
Khan, Azhar U. [1 ]
Khan, Masudulla [2 ]
Cho, Moo Hwan [3 ]
Khan, Mohammad Mansoob [4 ]
机构
[1] Jaipur Natl Univ, Sch Life & Basic Sci, Dept Chem, SIILAS CAMPUS, Jaipur 302017, Rajasthan, India
[2] Aligarh Muslim Univ, Dept Bot, Aligarh 202002, Uttar Pradesh, India
[3] Yeungnam Univ, Sch Chem Engn, Gyongsan 712749, Gyeongbuk, South Korea
[4] Univ Brunei Darussalam, Chem Sci, Fac Sci, Jalan Tungku Link, BE-1410 Gadong, Brunei
基金
新加坡国家研究基金会;
关键词
Nanostructures; Nanoparticles; Nanotechnology; Nanobiotechnology; Drug delivery; Medicines; Nanomedicines; Cancer; MAGNETIC NANOPARTICLES; SILVER NANOPARTICLES; GOLD NANOPARTICLES; CARBON NANOTUBES; GENE DELIVERY; QUANTUM DOTS; OXIDE NANOPARTICLES; CANCER-CHEMOTHERAPY; CONTRAST AGENTS; SYSTEMS;
D O I
10.1007/s00449-020-02330-8
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The development of nanoparticle-based drugs has provided many opportunities to diagnose, treat and cure challenging diseases. Through the manipulation of size, morphology, surface modification, surface characteristics, and materials used, a variety of nanostructures can be developed into smart systems, encasing therapeutic and imaging agents with stealth properties. These nanostructures can deliver drugs to specific tissues or sites and provide controlled release therapy. This targeted and sustained drug delivery decreases the drug-related toxicity and increases the patient's compliance with less frequent dosing. Nanotechnology employing nanostructures as a tool has provided advances in the diagnostic testing of diseases and cure. This technology has proven beneficial in the treatment of cancer, AIDS, and many other diseases. This review article highlights the recent advances in nanostructures and nanotechnology for drug delivery, nanomedicine and cures.
引用
收藏
页码:1339 / 1357
页数:19
相关论文
共 163 条
  • [1] Metallic nanoparticles: technology overview & drug delivery applications in oncology
    Ahmad, Mohammad Zaki
    Akhter, Sohail
    Jain, Gaurav Kumar
    Rahman, Mahfoozur
    Pathan, Shadab Ahmad
    Ahmad, Farhan Jalees
    Khar, Roop Krishen
    [J]. EXPERT OPINION ON DRUG DELIVERY, 2010, 7 (08) : 927 - 942
  • [2] Nanosponges - a completely new nano-horizon: pharmaceutical applications and recent advances
    Ahmed, Rana Z.
    Patil, Gunjan
    Zaheer, Zahid
    [J]. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2013, 39 (09) : 1263 - 1272
  • [3] PHARMACOKINETICS OF STEALTH VERSUS CONVENTIONAL LIPOSOMES - EFFECT OF DOSE
    ALLEN, TM
    HANSEN, C
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1068 (02) : 133 - 141
  • [4] Drug delivery systems: Entering the mainstream
    Allen, TM
    Cullis, PR
    [J]. SCIENCE, 2004, 303 (5665) : 1818 - 1822
  • [5] Liposomes - Opportunities in drug delivery
    Allen, TM
    [J]. DRUGS, 1997, 54 (Suppl 4) : 8 - 14
  • [6] LARGE UNILAMELLAR LIPOSOMES WITH LOW UPTAKE INTO THE RETICULOENDOTHELIAL SYSTEM
    ALLEN, TM
    CHONN, A
    [J]. FEBS LETTERS, 1987, 223 (01) : 42 - 46
  • [7] Antibody-drug conjugates: targeted drug delivery for cancer
    Alley, Stephen C.
    Okeley, Nicole M.
    Senter, Peter D.
    [J]. CURRENT OPINION IN CHEMICAL BIOLOGY, 2010, 14 (04) : 529 - 537
  • [8] In vivo imaging of gene and cell therapies
    Allport, JR
    Weissleder, R
    [J]. EXPERIMENTAL HEMATOLOGY, 2001, 29 (11) : 1237 - 1246
  • [9] Carbon nanotube reinforced Bombyx mori silk nanofibers by the electrospinning process
    Ayutsede, J
    Gandhi, M
    Sukigara, S
    Ye, HH
    Hsu, CM
    Gogotsi, Y
    Ko, F
    [J]. BIOMACROMOLECULES, 2006, 7 (01) : 208 - 214
  • [10] Quantum dot - Aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on Bi-fluorescence resonance energy transfer
    Bagalkot, Vaishali
    Zhang, Liangfang
    Levy-Nissenbaum, Etgar
    Jon, Sangyong
    Kantoff, Philip W.
    Langer, Robert
    Farokhzad, Omid C.
    [J]. NANO LETTERS, 2007, 7 (10) : 3065 - 3070