A comparison of NovaMin™ and casein phosphopeptide-amorphous calcium phosphate fluoride on enamel remineralization - An In vitro study using scanning electron microscope and DIAGNOdent®

Aim: The aim of this study was to compare the efficacy of NovaMin (TM) (SHY-NM) and casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) (tooth mousse plus (TM)) on enamel remineralization using DIAGNOdent (R) and scanning electron microscope (SEM). Methodology: Eighty-six natural permanent maxillary first premolars were selected and randomly divided into two groups of 43 each, Group A (NovaMin (TM)) and Group B (CPP-ACPF). All the samples were assessed using DIAGNOdent (R) (KaVo) at the baseline, after demineralization, and remineralization after 7 days. Two samples were randomly selected from each group after remineralization to evaluate the surface changes using SEM at x 1000 and x 2000. Results: The mean value of remineralization was highest for Group A NovaMin (TM) (6.56 +/- 0.93) compared to Group B, CPP-ACPF (tooth mousse plus (TM)) (6.02 +/- 1.09). The maximum demineralization to remineralization value within the groups showed that the mean values in Group B CPP-ACPF (7.02 +/- 3.02) was higher than Group A NovaMin (TM) (6.42 +/- 2.21). The difference in remineralizing potential between the groups and demineralization to remineralization value in within-group comparison was not found to be statistically significant. Conclusion: On comparing Group A NovaMin (TM) and Group B CPP-ACPF, Group B CPP-ACPF showed a higher amount of remineralization than Group A NovaMin (TM). From the present study, it can be inferred that both the experimental groups have the potential for remineralization.