Inhibitory effects of whisky congeners on melanogenesis in mouse B16 melanoma cells

被引：12
|
作者：
Ohguchi, Kenji [1 ]
Koike, Minako [2 ]
Suwa, Yoshihide [2 ]
Koshimizu, Seiichi [3 ]
Mizutani, Yuki [4 ]
Nozawa, Yoshinori [1 ]
Akao, Yukihiro [1 ]
机构：
[1] Gifu Int Inst Biotechnol, Gifu 5040838, Japan
[2] Suntory Ltd, Res Ctr, Osaka 6168503, Japan
[3] Suntory Ltd, Whisky Blending & Planning Dept, Osaka 6168503, Japan
[4] KOSE Corp, Div Res & Dev, Itabashi Ku, Tokyo 1740051, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2008年 / 72卷 / 04期
关键词：
whisky congeners; melanin; melanogenesis; tyrosinase;
D O I：
10.1271/bbb.70734
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We examined the effect of whisky congeners, substances other than ethanol in whisky, on melanogenesis in mouse B16 melanoma cells. Treatment with whisky congeners significantly blocked melanogenesis. Our results indicate that the inhibitory effects of whisky congeners on melanogenesis is due to direct inhibition of tyrosinase activity and to suppression of tyrosinase protein levels.
引用
收藏
页码：1107 / 1110
页数：4
相关论文
共 50 条
  • [21] Inhibitory Effects of Morinda citrifolia Extract and Its Constituents on Melanogenesis in Murine B16 Melanoma Cells
    Masuda, Megumi
    Itoh, Kimihisa
    Murata, Kazuya
    Naruto, Shunsuke
    Uwaya, Akemi
    Isami, Fumiyuki
    Matsuda, Hideaki
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2012, 35 (01) : 78 - 83
  • [22] Inhibitory Effect of Homochlorcyclizine on Melanogenesis in α-Melanocyte Stimulating Hormone-stimulated Mouse B16 Melanoma Cells
    Chang, Te-Sheng
    Chen, Chin-Tsun
    ARCHIVES OF PHARMACAL RESEARCH, 2012, 35 (01) : 119 - 127
  • [23] Stimulation of melanogenesis by glycyrrhizin in B16 melanoma cells
    Gi-Dong Jung
    Jeong-Yeh Yang
    Eun-Sup Song
    Jin-Woo Park
    Experimental & Molecular Medicine, 2001, 33 : 131 - 135
  • [24] Stimulation of melanogenesis by scoparone in B16 melanoma cells
    Yang, Jeong-yeh
    Koo, Jeung-hyun
    Song, Young-gil
    Kwon, Kang-beom
    Lee, Ju-hyung
    Sohn, Hee-sook
    Park, Byung-hyun
    Jhee, Eun-chung
    Park, Jin-woo
    ACTA PHARMACOLOGICA SINICA, 2006, 27 (11) : 1467 - 1473
  • [25] Stimulation of melanogenesis by scoparone in B16 melanoma cells
    Jeong-yeh YANG
    Jeung-hyunKOO
    Young-gilSONG
    Kang-beom KWON
    Ju-hyung LEE
    Hee-sook SOHN
    Byung-hyun PARK
    Eun-chung JHEE
    Jin-woo PARK
    Acta Pharmacologica Sinica, 2006, (11) : 1467 - 1473
  • [26] Stimulation of melanogenesis by glycyrrhizin in B16 melanoma cells
    Jung, GD
    Yang, JY
    Song, ES
    Park, JW
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2001, 33 (03): : 131 - 135
  • [27] Effect of xanthohumol on melanogenesis in B16 melanoma cells
    Koo, Jeung-Hyun
    Kim, Hyoung Tae
    Yoon, Ha-Yong
    Kwon, Kang-Beom
    Choi, Il-Whan
    Jung, Sung Hoo
    Kim, Han-Uk
    Park, Byung-Hyun
    Park, Jin-Woo
    EXPERIMENTAL AND MOLECULAR MEDICINE, 2008, 40 (03): : 313 - 319
  • [28] Effect of xanthohumol on melanogenesis in B16 melanoma cells
    Jeung-Hyun Koo
    Hyoung Tae Kim
    Ha-Yong Yoon
    Kang-Beom Kwon
    Il-Whan Choi
    Sung Hoo Jung
    Han-Uk Kim
    Byung-Hyun Park
    Jin-Woo Park
    Experimental & Molecular Medicine, 2008, 40 : 313 - 319
  • [29] Stimulation of melanogenesis by scoparone in B16 melanoma cells
    Jeong-yeh Yang
    Jeung-hyun Koo
    Young-gil Song
    Kang-beom Kwon
    Ju-hyung Lee
    Hee-sook Sohn
    Byung-hyun Park
    Eun-chung Jhee
    Jin-woo Park
    Acta Pharmacologica Sinica, 2006, 27 : 1467 - 1473
  • [30] Melanogenesis inhibitory activities of diarylheptanoids fromalnus hirsuta turcz in B16 mouse melanoma cell
    Soo Min Cho
    Young Min Kwon
    Jae Hee Lee
    Kyu Hyeong Yon
    Min Won Lee
    Archives of Pharmacal Research, 2002, 25 : 885 - 888
12345