Dibromination of Cinnamamides with CBr4 Under Mild Conditions

被引：0

作者：

Luo, Zaigang ^{[1
]}

Liu, Shuai ^{[1
]}

Peng, Chengtong ^{[1
]}

Wang, Xiuxiu ^{[1
]}

Xu, Xuemei ^{[1
]}

机构：

[1] Anhui Univ Sci & Technol, Coll Chem Engn, State Key Lab Min Response & Disaster Prevent & C, Huainan 232001, Peoples R China

来源：

LETTERS IN ORGANIC CHEMISTRY | 2022年 / 19卷 / 01期

关键词：

Dibromination; cinnamamides; CBr4; dibrominated propanamides; radical reaction; synthesis; EFFICIENT BROMINATION; N-BROMOSUCCINIMIDE; ALKENES; CHLORINATION; HALOGENATION; COMBINATION; CATALYST; BROMIDE; OXONE; H2O2;

D O I：

10.2174/1570178618666210920114503

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel, mild and efficient protocol to synthesize dibrominated propanamides has been developed. The presented methodology provides several merits, such as easy-to-handle and stable brominated substrate, catalyst-free, additive-free, and facile experimental operation. The study on the preliminary mechanism indicated that a free radical pathway might be involved in the presented reaction.

引用

页码：59 / 63

页数：5

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