Dibromination of Cinnamamides with CBr4 Under Mild Conditions

被引:0
|
作者
Luo, Zaigang [1 ]
Liu, Shuai [1 ]
Peng, Chengtong [1 ]
Wang, Xiuxiu [1 ]
Xu, Xuemei [1 ]
机构
[1] Anhui Univ Sci & Technol, Coll Chem Engn, State Key Lab Min Response & Disaster Prevent & C, Huainan 232001, Peoples R China
关键词
Dibromination; cinnamamides; CBr4; dibrominated propanamides; radical reaction; synthesis; EFFICIENT BROMINATION; N-BROMOSUCCINIMIDE; ALKENES; CHLORINATION; HALOGENATION; COMBINATION; CATALYST; BROMIDE; OXONE; H2O2;
D O I
10.2174/1570178618666210920114503
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel, mild and efficient protocol to synthesize dibrominated propanamides has been developed. The presented methodology provides several merits, such as easy-to-handle and stable brominated substrate, catalyst-free, additive-free, and facile experimental operation. The study on the preliminary mechanism indicated that a free radical pathway might be involved in the presented reaction.
引用
收藏
页码:59 / 63
页数:5
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