LONG-TERM (LT) THERAPY OF A FARNESOID X RECEPTOR (FXR) AGONIST OBETICHOLIC ACID (OCA) MAINTAINS BIOCHEMICAL RESPONSE IN PRIMARY BILIARY CIRRHOSIS (PBC)

被引：3
|
作者：
Hirschfield, G. [1 ]
Kowdley, K. [2 ]
Mason, A. [3 ]
Luketic, V. [4 ]
Gordon, S. [5 ]
Vincent, C. [6 ]
Mayo, M. [7 ]
Pares, A. [8 ]
Chapman, R. [9 ]
Lindor, K. [10 ]
Esguerra, M.
Eliot, L. [11 ]
Shapiro, D.
机构：
[1] Univ Toronto, Toronto, ON, Canada
[2] Virginia Mason Med Ctr, Seattle, WA 98101 USA
[3] Univ Alberta, Edmonton, AB, Canada
[4] Virginia Commonwealth Univ, Richmond, VA USA
[5] Henry Ford Hlth Ctr, Detroit, MI USA
[6] Hop St Luc, CHUM, Montreal, PQ H2X 1P1, Canada
[7] UT SW Med Ctr, Dallas, TX USA
[8] Hosp Clin Barcelona, Barcelona, Spain
[9] John Radcliffe Hosp, Headington, England
[10] Mayo Clin, Rochester, MN USA
[11] LKAN Clin, San Diego, CA USA
来源：
JOURNAL OF HEPATOLOGY | 2012年 / 56卷
关键词：
D O I：
10.1016/S0168-8278(12)60964-7
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
952
引用
收藏
页码：S372 / S372
页数：1
相关论文
共 50 条
  • [21] Long-Term Obeticholic Acid Therapy Improves Histological Endpoints in Patients With Primary Biliary Cholangitis
    Bowlus, Christopher L.
    Pockros, Paul J.
    Kremer, Andreas E.
    Pares, Albert
    Forman, Lisa M.
    Drenth, Joost P. H.
    Ryder, Stephen D.
    Terracciano, Luigi
    Jin, Yuying
    Liberman, Alexander
    Pencek, Richard
    Iloeje, Uche
    MacConell, Leigh
    Bedossa, Pierre
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2020, 18 (05) : 1170 - +
  • [22] LONG-TERM FOLLOW-UP OF PATIENTS WITH PRIMARY BILIARY-CIRRHOSIS (PBC) ON COLCHICINE THERAPY
    ZIFRONI, A
    SCHAFFNER, F
    HEPATOLOGY, 1990, 12 (04) : 843 - 843
  • [23] Farnesoid X Receptor (FXR) Agonist Obeticholic Acid (OCA) Restores Liver Regeneration after Partial Hepatectomy in Bile Acid Deprived Rats but Does Not Overdrive Natural FXR Activation in the Physiologic Process of Liver Regeneration.
    Dahrenmoller, Carola
    Schaap, Frank G.
    Damink, Steven Olde, Sr.
    Van Mierlo, Kim
    Jansen, Peter L. M.
    Horsmans, Yves
    Leclercq, Isabelle A.
    HEPATOLOGY, 2018, 68 : 827A - 828A
  • [24] Early primary biliary cirrhosis: Biochemical response to treatment and prediction of long-term outcome
    Corpechot, Christophe
    Chazouilleres, Olivier
    Poupon, Raoul
    JOURNAL OF HEPATOLOGY, 2011, 55 (06) : 1361 - 1367
  • [25] THE NONSTEROIDAL FARNESOID X RECEPTOR (FXR) AGONIST CILOFEXOR IMPROVES LIVER BIOCHEMISTRY IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS (PBC): A PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED TRIAL
    Kowdley, Kris V.
    Minuk, Gerald Y.
    Pagadala, Mangesh R.
    Gulamhusein, Aliya
    Swain, Mark Gordon
    Neff, Guy W.
    Zogg, Donald
    Bowlus, Christopher L.
    Agarwal, Kosh
    Yoshida, Eric M.
    Li, Yao
    Li, Georgia
    Chung, Chuhan
    Subramanian, Mani
    Myers, Robert P.
    Sheikh, Aasim M.
    Shiffman, Mitchell L.
    Fickert, Peter
    HEPATOLOGY, 2019, 70 : 31A - 32A
  • [26] What is the influence of long-term ursodeoxycholic acid therapy in patients with primary biliary cirrhosis?
    Clark, Virginia C.
    Levy, Cynthia
    NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY, 2007, 4 (04): : 188 - 189
  • [27] What is the influence of long-term ursodeoxycholic acid therapy in patients with primary biliary cirrhosis?
    Virginia C Clark
    Cynthia Levy
    Nature Clinical Practice Gastroenterology & Hepatology, 2007, 4 : 188 - 189
  • [28] Biochemical Response to Ursodeoxycholic Acid Predicts Long-Term Outcome in Japanese Patients With Primary Biliary Cirrhosis: A Validation Study
    Azemoto, Nobuaki
    Kumagi, Teru
    Abe, Masanori
    Konishi, Ichiro
    Matsuura, Bunzo
    Hiasa, Yoichi
    Onji, Morikazu
    GASTROENTEROLOGY, 2011, 140 (05) : S918 - S918
  • [29] Primary biliary cirrhosis (PBC) - Autoimmune hepatitis (AIH) overlap syndrome: Long term outcome and response to therapy.
    Chazouilleres, O
    Wendum, D
    Poupon, R
    HEPATOLOGY, 2002, 36 (04) : 500A - 500A
  • [30] Long-term safety and efficacy of Obeticholic Acid Treatment in Primary Biliary Cirrhosis after more than 4 years of treatment
    Kowdley, Kris V.
    Shah, Hemant
    Mason, Andrew
    Luketic, Velimir A.
    Pencek, Richard
    Marmon, Tonya
    Shapiro, David
    Hooshmand-Rad, Roya
    HEPATOLOGY, 2015, 62 : 521A - 522A
12345