Facile and rapid one-step mass preparation of quantum-dot barcodes

被引:123
作者
Fournier-Bidoz, Sebastien [1 ,2 ]
Jennings, Travis L. [1 ,2 ]
Klostranec, Jesse M. [1 ,2 ]
Fung, Winnie [1 ,2 ]
Rhee, Alex [1 ,2 ]
Li, David [1 ,2 ]
Chan, Warren C. W. [1 ,2 ]
机构
[1] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G9, Canada
[2] Univ Toronto, Terrence Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3G9, Canada
关键词
barcodes; biosensors; fluorescence; multiplexing; quantum dots;
D O I
10.1002/anie.200800409
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Graph Presented) Barcoding made easy: Quantum-dot-based barcodes were synthesized using a new concentration-controlled flow-focusing process. This one-step method yields robust barcodes that outperform current technologies and can be used in multiplexed detection of protein and genetic markers. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:5577 / 5581
页数:5
相关论文
共 34 条
  • [1] The use of nanocrystals in biological detection
    Alivisatos, P
    [J]. NATURE BIOTECHNOLOGY, 2004, 22 (01) : 47 - 52
  • [2] [Anonymous], PHYS REV LETT
  • [3] Comparative examination of the stability of semiconductor quantum dots in various biochemical buffers
    Boldt, K
    Bruns, OT
    Gaponik, N
    Eychmüller, A
    [J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (05) : 1959 - 1963
  • [4] Distribution of CdSe quantum dots within swollen polystyrene microgel particles using confocal microscopy
    Bradley, M
    Bruno, N
    Vincent, B
    [J]. LANGMUIR, 2005, 21 (07) : 2750 - 2753
  • [5] Encoding microcarriers by spatial selective photobleaching
    Braeckmans, K
    De Smedt, SC
    Roelant, C
    Leblans, M
    Pauwels, R
    Demeester, J
    [J]. NATURE MATERIALS, 2003, 2 (03) : 169 - 173
  • [6] Preparation of silica encapsulated quantum dot encoded beads for multiplex assay and its properties
    Cao, YC
    Huang, ZL
    Liu, TC
    Wang, HQ
    Zhu, XX
    Wang, Z
    Zhao, YD
    Liu, MX
    Luo, QM
    [J]. ANALYTICAL BIOCHEMISTRY, 2006, 351 (02) : 193 - 200
  • [7] Biomolecular screening with encoded porous-silicon photonic crystals
    Cunin, F
    Schmedake, TA
    Link, JR
    Li, YY
    Koh, J
    Bhatia, SN
    Sailor, MJ
    [J]. NATURE MATERIALS, 2002, 1 (01) : 39 - 41
  • [8] (CdSe)ZnS core-shell quantum dots: Synthesis and characterization of a size series of highly luminescent nanocrystallites
    Dabbousi, BO
    RodriguezViejo, J
    Mikulec, FV
    Heine, JR
    Mattoussi, H
    Ober, R
    Jensen, KF
    Bawendi, MG
    [J]. JOURNAL OF PHYSICAL CHEMISTRY B, 1997, 101 (46) : 9463 - 9475
  • [9] Preparation, physical properties, on-bead binding assay and spectroscopic reliability of 25 barcoded polystyrene-poly(ethylene glycol) graft copolymers
    Fenniri, H
    Chun, S
    Ding, LH
    Zyrianov, Y
    Hallenga, K
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (35) : 10546 - 10560
  • [10] Finkel NH, 2004, ANAL CHEM, V76, p353A