Psoriasis and psoriatic arthritis induced in a patient treated with infliximab for Crohn's disease

被引：11

作者：

Tichy, Martin, Jr. ^{[1
]}

Tichy, Martin ^{[2
]}

Kopova, Renata ^{[1
]}

Sternbersky, Jan ^{[1
]}

Ditrichova, Dagmar ^{[1
]}

机构：

[1] Palacky Univ, Fac Med & Dent, Univ Hosp, Dept Dermatol & Venereol, Olomouc 77520, Czech Republic

[2] Palacky Univ, Fac Med & Dent, Univ Hosp, Dept Pathol, Olomouc 77520, Czech Republic

来源：

JOURNAL OF DERMATOLOGICAL TREATMENT | 2012年 / 23卷 / 03期

关键词：

adverse reaction; Crohn's disease; infliximab; psoriasis; psoriatic arthritis; SERIES;

D O I：

10.3109/09546634.2010.521811

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The induction of psoriasis as a side effect of treatment with TNF-alpha inhibitors is one of a few rare complications of treatment, the pathogenic mechanism of which has not yet been completely clarified. The clinical presentation of these reactions may show the typical characteristics of psoriasis, palmoplantar pustulosis and psoriasiform exanthema; the individual variations of which may combine to give different presentations in individual patients. We present the case of a patient who, after administration of infliximab indicated for Crohn's disease, developed not only skin manifestations but also those of psoriatic arthritis.

引用

页码：208 / 211

页数：4

共 7 条

[1] The clustering of other chronic inflammatory diseases in inflammatory bowel disease: A population-based study [J].

Bernstein, CN ;

Wajda, A ;

Blanchard, JF .

GASTROENTEROLOGY, 2005, 129 (03) :827-836

[2]

Cohen JD, 2007, J RHEUMATOL, V34, P380

[3] PSORIASIS INDUCED BY INFLIXIMAB IN A PATIENT SUFFERING FROM CROHN'S DISEASE [J].

Manni, E. ;

Barachini, P. .

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 2009, 22 (03) :841-844

[4] Connections between psoriasis and Crohn's disease [J].

Najarian, DJ ;

Gottlieb, AB .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2003, 48 (06) :805-821

[5] A comparative analysis of the molecular genetic processes in the pathogenesis of psoriasis and Crohn's disease [J].

Piruzian, E. S. ;

Ishkin, A. A. ;

Nikol'skaya, T. A. ;

Abdeev, R. M. ;

Bruskin, S. A. .

MOLECULAR BIOLOGY, 2009, 43 (01) :159-165

[6] Successful Treatment of Hidradenitis Suppurativa with Infliximab in a Patient Who Failed to Respond to Etanercept [J].

Poulin, Yves .

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY, 2009, 13 (04) :221-225

[7] Tumor necrosis factor-α inhibitor-induced psoriasis or psoriasiform exanthemata -: First 120 cases from the literature including a series of six new patients [J].

Wollina, Uwe ;

Hansel, Gesina ;

Koch, Andre ;

Schoenlebe, Jaqueline ;

Koestler, Erich ;

Haroske, Gunter .

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2008, 9 (01) :1-14

← 1 →