α-glucosidase inhibitory activity of triterpenoids from Cichorium intybus

被引：68
|
作者：
Atta-Ur-Rahman [1 ]
Zareen, Seema [1 ]
Choudhary, M. Iqbal [1 ]
Akhtar, M. Nadeern [1 ]
Khan, Shamsun Nahar [1 ]
机构：
[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan
来源：
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 05期
关键词：
D O I：
10.1021/np800001v
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new triterpenoids, 18 alpha, 19 beta-20(30)-taraxasten-3 beta,21 alpha-diol (cichoridiol) (1) and 17-epi-methyl-6-hydroxyangolensate (intybusoloid) (2), were obtained from the methanolic extract of seeds of Cichorium intybus along with 11 known compounds, lupeol (3), friedelin (4), beta-sitosterol (5), stigmasterol (6), betulinic acid (7), betulin (8), betulinaldehyde (9), syringic acid (10), vanillic acid (11) 6,7-dihydroxycoumarin (12), and methyl-alpha-D-galactopyranoside (13). Compounds 1, 1a, and 11 showed a good alpha-glucosidase inhibitory activity.
引用
收藏
页码：910 / 913
页数：4
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