Intramolecular Michael Reaction of tert-Butylsulfinyl Ketimines: Asymmetric Synthesis of 3-Substituted Indanones

被引：36

作者：

Fustero, Santos ^{[1
,2
]}

Rodriguez, Elsa ^{[1
]}

Herrera, Lidia ^{[1
]}

Asensio, Amparo ^{[1
]}

Maestro, Miguel A. ^{[3
]}

Barrio, Pablo ^{[1
]}

机构：

[1] Univ Valencia, Dept Quim Organ, E-46100 Burjassot, Spain

[2] Ctr Invest Principe Felipe, Lab Mol Organ, E-46012 Valencia, Spain

[3] Univ A Coruna, Dept Quim Fundamental, La Coruna 15071, Spain

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 24期

关键词：

ENANTIOSELECTIVE SYNTHESIS; DIASTEREOSELECTIVE SYNTHESIS; ACTIVATION;

D O I：

10.1021/ol2028948

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aromatic tert-butylsulfinyl ketimines bearing a suitable Michael acceptor at the ortho position readily undergo an intramolecular conjugate addition achieving indanone derivatives in good yields and complete diastereoselectivity.

引用

页码：6564 / 6567

页数：4

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