Antimelanogenic and antioxidative properties of Bifidobacterium bifidum

被引：8

作者：

Huang, Huey-Chun ^{[3
]}

Huang, Wen-Ying ^{[1
,2
]}

Chiu, Shao-Hua ^{[1
,2
]}

Ke, Hui-Ju ^{[1
,2
]}

Chiu, Shu-wen ^{[1
,2
]}

Wu, Sze-Yun ^{[1
,2
]}

Kuo, Feng-Sheng ^{[1
,2
]}

Chang, Tsong-Min ^{[1
,2
]}

机构：

[1] Hungkuang Univ, Dept Appl Cosmetol, Shalu 43302, Taichung County, Taiwan

[2] Hungkuang Univ, Grad Inst Cosmet Sci, Shalu 43302, Taichung County, Taiwan

[3] China Med Univ, Dept Med Lab Sci & Biotechnol, Taichung, Taiwan

来源：

ARCHIVES OF DERMATOLOGICAL RESEARCH | 2011年 / 303卷 / 07期

关键词：

Bifidobacterium bifidum; Tyrosinase; Melanin; Antioxidant; OXIDATIVE STRESS; TYROSINASE; EXPRESSION; MELANOGENESIS;

D O I：

10.1007/s00403-011-1135-y

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Various skin hyperpigmentation disorders consist in accumulation and overproduction of melanin. In this report, we investigated the melanogenesis inhibitory and antioxidant effects of Bifidobacterium bifidum culture filtrate. The results revealed that B. bifidum culture filtrate effectively suppresses murine tyrosinase activity and decreases the amount of intracellular melanin in a dose-dependent manner. Additionally, the bacterial culture filtrate-scavenged DPPH and ABTS radicals, and shows potent-reducing power in a dose-dependent pattern. Our results expand the application of B. bifidum culture filtrate in the development and research of skin-whitening ingredients.

引用

页码：527 / 531

页数：5

共 20 条

[1] BMP-2 stimulates tyrosinase gene expression and melanogenesis in differentiated melanocytes [J].