Synthesis of [1,2,3]Triazolo-[1,5-a]quinoxalin-4(5H)-ones through Photoredox-Catalyzed [3+2] Cyclization Reactions with Hypervalent lodine(III) Reagents

被引：35

作者：

Wen, Jinxia ^{[1
]}

Zhao, Wenyan ^{[1
]}

Gao, Xu ^{[1
]}

Ren, Xiaofang ^{[1
]}

Dong, Chunping ^{[1
]}

Wang, Cheli ^{[1
]}

Liu, Li ^{[1
]}

Li, Jian ^{[1
]}

机构：

[1] Changzhou Univ, Sch Pharm, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 87卷 / 06期

关键词：

ARYL ACYL PEROXIDES; CLICK CHEMISTRY; TRIAZOLE DERIVATIVES; QUINOXALIN-2(1H)-ONES; METAL; ACCESS; ARYLATION; BENZODIAZEPINE; QUINOXALINONES; PHOTOCATALYST;

D O I：

10.1021/acs.joc.2c00135

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of a variety of [1,2,3]triazolo-[1,5-a]quinoxalin-4(5H)-ones via a [3 + 2] cyclization reaction by photoredox catalysis between quinoxalinones and hypervalent iodine(III) reagents is reported. A range of quinoxalinones and hypervalent iodine(III) reagents were tolerated well. This cyclization reaction allows access to structurally diverse [1,2,3]triazolo-[1,5-a]quinoxalin-4(SH)-ones in moderate to good yields.

引用

页码：4415 / 4423

页数：9

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