Optimization and scale-up of pharmaceutical syntheses

被引：0
|
作者：
Les, Andrzei [1 ]
Szelejewski, Wieslaw [1 ]
机构：
[1] Inst Farmaceut, PL-01793 Warsaw, Poland
来源：
PRZEMYSL CHEMICZNY | 2007年 / 86卷 / 12期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Five case studies on optimization and scale-up of the pharmaceutical syntheses recently developed were presented. Details of methodol. approach were given for the syntheses of aripiprazole and pramipexole, while the syntheses of lamotrigine, pioglitazone and anthracycline sugar synthon were outlined only.
引用
收藏
页码：1174 / 1177
页数：4
相关论文
共 50 条
  • [21] Application of process modelling tools in the scale-up of pharmaceutical crystallisation processes
    Schmidt, B
    Patel, J
    Ricard, FX
    Brechtelsbauer, CM
    Lewis, N
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2004, 8 (06) : 998 - 1008
  • [22] Optimization and scale-up of the alkaline lysis step.
    Kelly, WJ
    Clemson, M
    Fredette, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U223 - U223
  • [23] Extrusion Scale-up: An Optimization-based Methodology
    Covas, J. A.
    Gaspar-Cunha, A.
    INTERNATIONAL POLYMER PROCESSING, 2009, 24 (01) : 67 - 82
  • [24] Scale-up and productivity optimization for protein a chromatography.
    Shukla, AA
    Hinckley, P
    Hubbard, B
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U215 - U215
  • [25] Continuous flow azide formation: Optimization and scale-up
    Delville, Marielle M. E.
    Nieuwland, Pieter J.
    Janssen, Paul
    Koch, Kaspar
    van Hest, Jan C. M.
    Rutjes, Floris P. J. T.
    CHEMICAL ENGINEERING JOURNAL, 2011, 167 (2-3) : 556 - 559
  • [26] Optimization of Two Steps in Scale-Up Synthesis of Nannocystin A
    Zhang, Tingrong
    Miao, Shaojie
    Zhang, Mingxiao
    Liu, Wenjie
    Wang, Liang
    Chen, Yue
    MARINE DRUGS, 2021, 19 (04)
  • [27] PROCESS OPTIMIZATION AND SCALE-UP OF BACTERIAL ICE NUCLEATION
    WARD, PJ
    LYNN, SY
    LAWLESS, RJ
    HENDRICKS, DM
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1989, 198 : 217 - MBTD
  • [28] Optimization and scale-up of bioreactor for mammalian cell culture
    Kamekura, Koichi
    Iso, Yoshiyuki
    Iwasa, Yoshitaka
    Ooki, Takamasa
    Sugaya, Kazuo
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2009, 108 : S7 - S7
  • [29] Scale-up of a pharmaceutical granulation in fixed bowl mixer-granulators
    Landin, M
    York, P
    Cliff, MJ
    Rowe, RC
    Wigmore, AJ
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1996, 133 (1-2) : 127 - 131
  • [30] Generative PAT Fingerprint Approach for Verification of the Scale-Up of Pharmaceutical Processes
    Dijkmans, Jan
    Chau, Joris
    Maes, Tor
    Khamiakova, Tatsiana
    Laps, Stijn
    Vandervoort, Niels
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2024, 28 (03) : 770 - 779
12345