Quality and safety investigation of commonly used topical cosmetic preparations

被引:9
作者
Almukainzi, May [1 ]
Alotaibi, Lubna [2 ]
Abdulwahab, Anfal [2 ]
Albukhary, Nada [2 ]
El Mahdy, Areej M. [1 ,3 ]
机构
[1] Princess Nourah bint Abdulrahman Univ, Coll Pharm, Dept Pharmaceut Sci, POB 84428, Riyadh 11671, Saudi Arabia
[2] Princess Nourah bint Abdulrahman Univ, Coll Pharm, Riyadh, Saudi Arabia
[3] Mansoura Univ, Fac Pharm, Dept Microbiol & Immunol, Mansoura, Egypt
关键词
CONTAMINATION; INFECTIONS; MANAGEMENT; METALS;
D O I
10.1038/s41598-022-21771-7
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Cosmetic and personal care products are considered an essential part of our daily care routine; hence, these products must be stable and safe for human use. This study aimed to assess the quality and safety of the most common cosmetic preparations. To select the products to be tested, a cross-sectional survey was distributed featuring the most used types and brands of products. Based on 447 responses from both males and females with different ages and education levels, 21 products from different brands were selected and tested in terms of microbial load, heavy metal content, and organoleptic properties. Microbial contamination was investigated using the aerobic plate count method. Lead (Pb), aluminum (Al), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), manganese (Mn), nickel (Ni), zinc (Zn), iron (Fe), and arsenic (As) impurities were analyzed using an inductively coupled plasma mass spectrometer. The products included sunblock, lip balm, hand cream, hair cream, shampoo, cleanser, baby oil, baby powder, bar soap, hair dye, makeup, deodorant, hair serum, shaving gel, and toothpaste. Microbial contamination was found in 14 of the products, ranging between 1467.5 and 299.5 cfu/ml. The most commonly isolated microorganisms were Staphylococcus aureus and Bacillus species. Most of the tested products showed metal impurities, with toothpaste having the highest concentrations of Pb, Cr, As, Cu and Ni. The samples did not show lumps or discoloration, did not have characteristic odors, and had pH values ranging from 6.90 to 8.10. The continuous usage of such products could lead to serious negative consequences. As a result, ensuring the quality of cosmetic products is critical. Regulatory authorities are required to enforce strict legislation on cosmetic manufacturing to assess and ensure the quality and safety of the products before they reach consumers.
引用
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页数:11
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