Changes in Bihemispheric Structural Connectivity Following Middle Cerebral Artery Infarction

被引:1
作者
Kim, Dae Hyun [1 ]
Kang, Hyunkoo [2 ]
机构
[1] Yonsei Univ, Coll Med, Dept & Res Inst Rehabil Med, Seoul 03722, South Korea
[2] Med Ctr, Vet Hlth Serv, Dept Radiol, Seoul 05368, South Korea
基金
新加坡国家研究基金会;
关键词
stroke; recovery; lateralization; structural connectivity; MOTOR RECOVERY; UNAFFECTED HEMISPHERE; STROKE; DISINHIBITION; DIASCHISIS; MECHANISMS; CORTEX;
D O I
10.3390/jpm12010081
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
This study investigated the changes in the structural connectivity of the bilateral hemispheres over time following a middle cerebral artery infarction. Eighteen patients in the subacute group and nine patients in the chronic group with mild upper extremity motor impairment (Fugl-Meyer motor assessment score for the upper limb > 43) following middle cerebral artery infarction were retrospectively evaluated in this study. All the patients underwent T1-weighted and diffusion tensor imaging. Tract-based statistical analyses of fractional anisotropy were used to compare the changes in the bilateral structural connectivity with those of age-matched normal controls. The corticospinal tract pathway of the affected hemisphere, corpus callosum, and corona radiata of the unaffected hemisphere had decreased structural connectivity in the subacute group, while the motor association area and anterior corpus callosum in the bilateral frontal lobes had increased structural connectivity in the chronic group. The bilateral hemispheres were influenced even in patients with mild motor impairment following middle cerebral artery infarction, and the structural connectivity of the bilateral hemispheres changed according to the time following the stroke.
引用
收藏
页数:7
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