Non-fatal mirtazapine overdose

被引：20
作者：
Retz, W
Maier, S
Maris, F
Rösler, M
机构：
[1] Univ Wurzburg, Dept Psychiat, D-97080 Wurzburg, Germany
[2] Univ Wurzburg, Dept Internal Med, D-97080 Wurzburg, Germany
来源：
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1998年 / 13卷 / 06期
关键词：
mirtazapine; overdose; plasma-level; hypothermia;
D O I：
10.1097/00004850-199811000-00007
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
We report the case of intoxication of a 41-year-old female patient suffering from major depression with mirtazapine complicated by severe hypothermia. The patient was brought to an intensive care unit 10 hours after intake of 1200 mg mirtazapine and 20 mg lorazepam and laying outside at outdoor temperatures below 0 degrees C. The mirtazapine plasma-level was 368 ng/ml still after 41 hours. Body temperature was reduced to 26 degrees C and rhabdomyolysis due to hypothermia was observed. Cardial and respiratory function was compromised and intubation was necessary. The patient recovered without persisting somatic impairment. Int Clin Psychopharmacol 13:277-279 (C) 1998 Lippincott Williams & Wilkins.
引用
收藏
页码：277 / 279
页数：3
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