Synthesis and characterization of the monomer ruthenium complex of hypocrellin B

被引：19
作者：
Zhou, JH
Liu, JH
Feng, YY
Wei, SH
Gu, XT
Wang, XS [1 ]
Zhang, BW
机构：
[1] Nanjing Normal Univ, Anal & Testing Ctr, Nanjing 210097, Peoples R China
[2] Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100101, Peoples R China
[3] China Pharmaceut Univ, Dept Complex Presect CMM, Nanjing 210038, Peoples R China
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 12期
关键词：
hypocrellin B; complex;
D O I：
10.1016/j.bmcl.2005.04.035
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
We first synthesized and characterized a monomer ruthenium complex of hypocrellin B (HB) by chelation with Ru-(bpy)(2)Cl-2 (in which bpy = 2,2'-bipyridine). It possesses the photosensitizing properties and can be applied in photodynamic therapy (PDT). The chemiluminescence assays indicated that the photodamage ability of the complex is stronger than that of HB. (c) 2005 Elsevier Ltd. All rights reserved.
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收藏
页码：3067 / 3070
页数：4
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