Biocompatible dispersions of carbon nanotubes: a potential tool for intracellular transport of anticancer drugs

被引：32
作者：
Di Crescenzo, Antonello [1 ]
Velluto, Diana [2 ,3 ]
Hubbell, Jeffrey A. [2 ,3 ]
Fontana, Antonella [1 ]
机构：
[1] Univ G DAnnunzio, Dipartimento Sci Farmaco, I-66013 Chieti, Italy
[2] Ecole Polytech Fed Lausanne, Inst Bioengn, CH-1015 Lausanne, Switzerland
[3] Ecole Polytech Fed Lausanne, Inst Chem Sci & Engn, CH-1015 Lausanne, Switzerland
来源：
NANOSCALE | 2011年 / 3卷 / 03期
关键词：
SINGLE-WALL; BIOMEDICAL APPLICATIONS; DELIVERY; FLUORESCENCE; DOXORUBICIN; GLYCOL; FUNCTIONALIZATION; SOLUBILIZATION; COPOLYMERS; CHEMISTRY;
D O I：
10.1039/c0nr00444h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The use of the biocompatible amphiphilic diblock copolymer poly (ethylene glycol-b-propylene sulfide) (PEG(44)PPS(20)) allows a tuned loading of doxorubicin onto the surface of non-functionalized multi-walled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.
引用
收藏
页码：925 / 928
页数：4
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