Correlation between extreme fear and focal cortical dysplasia in anterior cingulate gyrus: Evidence from a surgical case of refractory epilepsy

被引：8

作者：

Qiao, Liang ^{[1
]}

Yu, Tao ^{[1
]}

Ni, Duanyu ^{[1
]}

Wang, Xueyuan ^{[1
]}

Xu, Cuiping ^{[1
]}

Liu, Chang ^{[1
]}

Zhang, Guojun ^{[1
]}

Li, Yongjie ^{[1
]}

机构：

[1] Capital Med Univ, Xuanwu Hosp, Beijing Inst Funct Neurosurg, Beijing 100053, Peoples R China

来源：

CLINICAL NEUROLOGY AND NEUROSURGERY | 2017年 / 163卷

关键词：

Fear; Focal cortical dysplasia; Anterior cingulate gyrus; Surgery; Refractory epilepsy; TEMPORAL-LOBE EPILEPSY; AMYGDALA;

D O I：

10.1016/j.clineuro.2017.10.025

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Localizing the semiology of ictal fear and seizure onset in epilepsy patients is commonly challenging due to limited value of routine electroencephalography (EEG) and very few surgical attempts. Here we reported a case of refractory epilepsy characterized by aura of extreme fear and hypermotor seizures, in which the left (dominant hemisphere) anterior cingulate gyrus (ACG) was determined to be the epileptogenic zone (EZ) through multiple modalities of presurgical evaluation including analysis of high frequency oscillation on intracranial EEG. Tailored resection of EZ was thus performed and pathological examination revealed focal cortical dysplasia (FCD) type lib. The patient has been seizure free during an 18-month follow-up. The report has provided novel anatomical, electrophysiological and surgical evidences suggesting the critical role of ACG in ictal fear and possibility of surgical management of fear-manifesting refractory epilepsy.

引用

页码：121 / 123

页数：3

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