Development and characterization of xyloglucan-poly(vinyl alcohol) hydrogel membrane for Wireless Smart wound dressings

被引：23

作者：

Ajovalasit, Alessia ^{[1
]}

Caccami, Maria Cristina ^{[2
]}

Amendola, Sara ^{[3
]}

Sabatino, Maria Antonietta ^{[1
]}

Alotta, Gioacchino ^{[4
]}

Zingales, Massimiliano ^{[4
]}

Giacomazza, Daniela ^{[5
]}

Occhiuzzi, Cecilia ^{[3
]}

Marrocco, Gaetano ^{[2
,3
]}

Dispenza, Clelia ^{[1
,5
]}

机构：

[1] Univ Palermo, DIID, Viale Sci Ed 6, I-90128 Palermo, Italy

[2] Univ Roma Tor Vergata, Dipartimento Ingn Civile & Informat, Via Politecn 1, I-00133 Rome, Italy

[3] Univ Roma Tor Vergata, RADIO6ENSE Srl, Via Politecn 1, I-00133 Rome, Italy

[4] Univ Palermo, Dipartimento Ingn Civile Ambientale Aerosp & Mat, Viale Sci Ed 8, I-90128 Palermo, Italy

[5] CNR, Ist BioFis IBF, Via U La Malfa 153, I-90146 Palermo, PA, Italy

来源：

EUROPEAN POLYMER JOURNAL | 2018年 / 106卷

关键词：

Hydrogels; Wound dressings; Dielectric properties; Swelling; RFID sensors; Epidermal electronics; POLYSACCHARIDE; PRINCIPLES; MEDICINE; ANTENNAS; SENSORS; SKIN;

D O I：

10.1016/j.eurpolymj.2018.07.038

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Hydrogel-based smart wound dressings that combine the traditional favourable properties of hydrogels as skin care materials with sensing functions of relevant biological parameters for the remote monitoring of wound healing are under development. In particular, lightweight, ultra-high frequency radiofrequency identification (UHF RFID) sensor are adjoined to xyloglucan-poly(vinyl alcohol) hydrogel films to battery-less monitor moisture level of the bandage in contact with the skin, as well as wireless transmit the measured data to an off-body reader. This study investigates the swelling behavior of the hydrogels in contact with simulated biological fluids, and the modification of their morphology, mechanical properties, and dielectric properties in a wide range of frequencies (10(0)-10(6) Hz and 10(8) -10(11) Hz). The films absorb simulated body fluids up to approximately four times their initial weight, without losing their integrity but undergoing significant microstructural changes. We observed relevant linear increases of electric conductivity and permittivity with the swelling degree, with an abrupt change of slope that is related to the network rearrangements occurring upon swelling.

引用

页码：214 / 222

页数：9

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