The potential of alkaloids in drug discovery

被引：258

作者：

Cordell, GA ^{[1
]}

Quinn-Beattie, ML ^{[1
]}

Farnsworth, NR ^{[1
]}

机构：

[1] Univ Illinois, Coll Pharm, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA

来源：

PHYTOTHERAPY RESEARCH | 2001年 / 15卷 / 03期

关键词：

alkaloids; drug discovery; taxonomic distribution; biological evaluation; future developments;

D O I：

10.1002/ptr.890

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Alkaloids are an important group of diversely distributed, chemically, biologically and commercially significant natural products. This article suggests why now, with the presently available technology, and the remaining biome available and reasonably accessible, is an opportune moment to consciously focus on the discovery of further alkaloids with pharmacophoric utility.

引用

页码：183 / 205

页数：23

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