Systemic Thrombolysis for Ischemic Stroke after Antagonizing Dabigatran with Idarucizumab-A Case Report

被引：32

作者：

Schaefer, Niklas ^{[1
]}

Mueller, Andreas ^{[2
]}

Wuellner, Ullrich ^{[1
]}

机构：

[1] Univ Bonn, Med Ctr, Dept Neurol, Sigmund Freud Str 25, D-53127 Bonn, Germany

[2] Univ Bonn, Med Ctr, Dept Neuroradiol, Bonn, Germany

来源：

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | 2016年 / 25卷 / 08期

关键词：

Idarucizumab; ischemic stroke; dabigatran; atrial fibrillation; systemic thrombolysis; REVERSAL;

D O I：

10.1016/j.jstrokecerebrovasdis.2016.05.006

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We here describe our experience of systemic thrombolysis therapy for severe ischemic stroke in a patient taking dabigatran for atrial fibrillation. After administration of the monoclonal antibody fragment idarucizumab, the anticoagulative effects of dabigatran were efficiently antagonized and application of alteplase was safe and feasible in our patient. This case report may illustrate a novel treatment option in the neurological emergency setting.

引用

页码：E126 / E127

页数：2

共 2 条

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