Outcomes following cardioversion for patients with cardiac amyloidosis and atrial fibrillation or atrial flutter

被引：10

作者：

Loungani, Rahul S. ^{[1
]}

Rehorn, Michael R. ^{[1
]}

Geurink, Kyle R. ^{[1
]}

Coniglio, Amanda C. ^{[1
]}

Black-Maier, Eric ^{[1
]}

Pokorney, Sean D. ^{[1
,2
]}

Khouri, Michel G. ^{[1
]}

机构：

[1] Duke Univ, Div Cardiovasc Dis, Med Ctr, Durham, NC USA

[2] Duke Univ, Duke Clin Res Inst, Electrophysiol Sect, Med Ctr, Durham, NC USA

来源：

AMERICAN HEART JOURNAL | 2020年 / 222卷

关键词：

ARRHYTHMIAS;

D O I：

10.1016/j.ahj.2020.01.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial arrhythmias commonly occur in patients with cardiac amyloidosis (CA), but there is limited data on safety or efficacy of cardioversion (DCCV) for management of these rhythms in CA. We identified 25 patients with CA (20 with transthyretin (TTR) and 5 with light-chain (AL) amyloidosis) at Duke University who underwent DCCV for atrial arrhythmias and documented procedural success, complications, and long-term morbidity and mortality. While DCCV successfully restored sinus rhythm in 96% of patients, 36% of patients experienced immediate procedural complications (primarily bradycardia and hypotension), 80% had recurrence of atrial arrhythmias at 1 year, and 52% died at 3 years, highlighting short-term safety concerns, long-term inefficacy, and poor prognosis associated with symptomatic atrial arrhythmias requiring DCCV in CA.

引用

页码：26 / 29

页数：4

共 10 条

[1] Electrophysiologic assessment of conduction abnormalities and atrial arrhythmias associated with amyloid cardiomyopathy [J].

Barbhaiya, Chirag R. ;

Kumar, Saurabh ;

Baldinger, Samuel H. ;

Michaud, Gregory F. ;

Stevenson, William G. ;

Falk, Rodney ;

John, Roy M. .

HEART RHYTHM, 2016, 13 (02) :383-390

[2] Optimal heart failure therapy and successful cardioversion in heart failure patients with atrial fibrillation [J].

Boldt, Leif-Hendrik ;

Rolf, Sascha ;

Huemer, Martin ;

Parwani, Abdul Shokor ;

Luft, Friedrich C. ;

Dietz, Rainer ;

Haverkamp, Wilhehn .

AMERICAN HEART JOURNAL, 2008, 155 (05) :890-895

[3] Serum cardiac troponins and N-terminal pro-brain natriuretic peptide: A staging system for primary systemic amyloidosis [J].

Dispenzieri, A ;

Gertz, MA ;

Kyle, RA ;

Lacy, MQ ;

Burritt, MF ;

Therneau, TM ;

Greipp, PR ;

Witzig, TE ;

Lust, JA ;

Rajkumar, SV ;

Fonseca, R ;

Zeldenrust, SR ;

McGregor, CGA ;

Jaffe, AS .

JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (18) :3751-3757

[4] Direct Current Cardioversion of Atrial Arrhythmias in Adults With Cardiac Amyloidosis [J].

El-Am, Edward A. ;

Dispenzieri, Angela ;

Melduni, Rowlens M. ;

Ammash, Naser M. ;

White, Roger D. ;

Hodge, David O. ;

Noseworthy, Peter A. ;

Lin, Grace ;

Pislaru, Sorin V. ;

Egbe, Alexander C. ;

Grogan, Martha ;

Nkomo, Vuyisile T. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 73 (05) :589-597

[5] Atrial fibrillation in amyloidotic cardiomyopathy: prevalence, incidence, risk factors and prognostic role [J].

Longhi, Simone ;

Quarta, Candida Cristina ;

Milandri, Agnese ;

Lorenzini, Massimiliano ;

Gagliardi, Christian ;

Manuzzi, Lisa ;

Bacchi-Reggiani, Maria Letizia ;

Leone, Ornella ;

Ferlini, Alessandra ;

Russo, Antonio ;

Gallelli, Ilaria ;

Rapezzi, Claudio .

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2015, 22 (03) :147-155

[6] Catheter Ablation for Atrial Fibrillation with Heart Failure [J].

Marrouche, Nassir F. ;

Brachmann, Johannes ;

Andresen, Dietrich ;

Siebels, Juergen ;

Boersma, Lucas ;

Jordaens, Luc ;

Merkely, Bela ;

Pokushalov, Evgeny ;

Sanders, Prashanthan ;

Proff, Jochen ;

Schunkert, Heribert ;

Christ, Hildegard ;

Vogt, Juergen ;

Baensch, Dietmar .

NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (05) :417-427

[7] Genotype and Phenotype of Transthyretin Cardiac Amyloidosis THAOS (Transthyretin Amyloid Outcome Survey) [J].

Maurer, Mathew S. ;

Hanna, Mazen ;

Grogan, Martha ;

Dispenzieri, Angela ;

Witteles, Ronald ;

Drachman, Brian ;

Judge, Daniel P. ;

Lenihan, Daniel J. ;

Gottlieb, Stephen S. ;

Shah, Sanjiv J. ;

Steidley, D. Eric ;

Ventura, Hector ;

Murali, Srinivas ;

Silver, Marc A. ;

Jacoby, Daniel ;

Fedson, Savitri ;

Hummel, Scott L. ;

Kristen, Arnt V. ;

Damy, Thibaud ;

Plante-Bordeneuve, Violaine ;

Coelho, Teresa ;

Mundayat, Rajiv ;

Suhr, Ole B. ;

Cruz, Marcia Waddington ;

Rapezzi, Claudio .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 68 (02) :161-172

[8] Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience [J].

Mints, Yuliya Y. ;

Doros, Gheorghe ;

Berk, John L. ;

Connors, Lawreen H. ;

Ruberg, Frederick L. .

ESC HEART FAILURE, 2018, 5 (05) :772-779

[9] Transthyretin Amyloid Cardiomyopathy JACC State-of-the-Art Review [J].

Ruberg, Frederick L. ;

Grogan, Martha ;

Hanna, Mazen ;

Kelly, Jeffery W. ;

Maurer, Mathew S. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 73 (22) :2872-2891

[10] Outcomes After Nonemergent Electrical Cardioversion for Atrial Arrhythmias [J].

Steinberg, Benjamin Adam ;

Schulte, Phillip Joel ;

Hofmann, Paul ;

Ersboll, Mads ;

Alexander, John Hunter ;

Broderick-Forsgren, Kathleen ;

Anstrom, Kevin Joseph ;

Granger, Christopher Bull ;

Piccini, Jonathan Paul ;

Velazquez, Eric Jose ;

Shah, Bimal Ramesh .

AMERICAN JOURNAL OF CARDIOLOGY, 2015, 115 (10) :1407-1414

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