Violacein and its antifungal activity: comments and potentialities

被引：22

作者：

Duran, N. ^{[1
,2
]}

Castro, G. R. ^{[2
,3
]}

Portela, R. W. D. ^{[4
]}

Favaro, W. J. ^{[1
]}

Duran, M. ^{[1
]}

Tasic, L. ^{[5
]}

Nakazato, G. ^{[6
]}

机构：

[1] Univ Estadual Campinas UNICAMP, Dept Struct & Funct Biol, Lab Urogenital Carcinogenesis & Immunotherapy, Campinas, SP, Brazil

[2] Univ Fed ABC UFABC, Ctr Nat & Human Sci CCNH, Nanomed Res Unit Nanomed, Santo Andre, SP, Brazil

[3] Univ Nacl Rosario, Max Planck Lab Struct Biol Chem & Mol Biophys Ros, Max Planck Inst Biophys Chem MPIbpC,Partner Lab, MPG,Ctr Estudios Interdisciplinarios CEI,UNR MPIb, Rosario, Santa Fe, Argentina

[4] Univ Fed Bahia, Hlth Sci Inst, Lab Immunol & Mol Biol, Salvador, BA, Brazil

[5] Univ Estadual Campinas UNICAMP, Inst Chem, Biog Chem Lab, Campinas, SP, Brazil

[6] Univ Estadual Londrina UEL, Biol Sci Ctr, Dept Microbiol, Lab Basic & Appl Bacteriol, Londrina, Puerto Rico, Brazil

来源：

LETTERS IN APPLIED MICROBIOLOGY | 2022年 / 75卷 / 04期

基金：

巴西圣保罗研究基金会;

关键词：

antifungal drug; antimicrobial pigment; Chromobacterium violaceum; fungal resistance; Janthinobacterium lividum; violacein; CHROMOBACTERIUM-VIOLACEUM; METABOLITE; DRUG; RESISTANCE; BACTERIA; AGENTS;

D O I：

10.1111/lam.13760

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Violacein is an important natural antimicrobial pigment that is mainly produced by Chromobacterium violaceum and Janthinobacterium lividum. It presents a significant range of effects against phytopathogenic and human fungi, besides being featured as having low toxicity, and by its important ecological role in protecting amphibian species and applications in dyed medical fabric. The hypothesis about violacein's action mechanisms against mucormycosis (Rhizopus arrhizus) and candidiasis (Candida auris) is herein discussed based on data available in the scientific literature.

引用

页码：796 / 803

页数：8

共 61 条

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