Single-beam coherent Raman spectroscopy and microscopy via spectral notch shaping

被引：42

作者：

Katz, Ori ^{[1
]}

Levitt, Jonathan M. ^{[1
]}

Grinvald, Eran ^{[1
]}

Silberberg, Yaron ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Phys Complex Syst, IL-76100 Rehovot, Israel

来源：

OPTICS EXPRESS | 2010年 / 18卷 / 22期

基金：

以色列科学基金会;

关键词：

SCATTERING MICROSCOPY; CARS MICROSCOPY; PULSE; EXTRACTION; STANDOFF;

D O I：

10.1364/OE.18.022693

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present a simple and easily implementable scheme for multiplexed Coherent Anti-Stokes Raman Scattering (CARS) spectroscopy and microscopy using a single femtosecond pulse, shaped with a narrow spectral notch. We show that a tunable spectral notch, shaped by a resonant photonic crystal slab, can serve as a narrowband, optimally time-delayed probe, resolving a broad vibrational spectrum with high spectral resolution in a single-shot measurement. Our single-source, single-beam scheme allows the simple transformation of any multiphoton microscope with adequate bandwidth into a nearly alignment-free CARS microscope. (C) 2010 Optical Society of America

引用

页码：22693 / 22701

页数：9

共 30 条

[1] Invited Review Article: Imaging techniques for harmonic and multiphoton absorption fluorescence microscopy [J].

Carriles, Ramon ;

Schafer, Dawn N. ;

Sheetz, Kraig E. ;

Field, Jeffrey J. ;

Cisek, Richard ;

Barzda, Virginijus ;

Sylvester, Anne W. ;

Squier, Jeffrey A. .

REVIEW OF SCIENTIFIC INSTRUMENTS, 2009, 80 (08)

[2] Optimal laser pulse shaping for interferometric multiplex coherent anti-stokes Raman scattering microscopy [J].

Chen, Bi-Chang ;

Lim, Sang-Hyun .

JOURNAL OF PHYSICAL CHEMISTRY B, 2008, 112 (12) :3653-3661

[3] NONLINEAR PULSE SHAPING AND CAUSALITY [J].

DASILVA, VL ;

SILBERBERG, Y ;

HERITAGE, JP .

OPTICS LETTERS, 1993, 18 (08) :580-582

[4] Single-pulse coherent anti-Stokes Raman spectroscopy in the fingerprint spectral region [J].

Dudovich, N ;

Oron, D ;

Silberberg, Y .

JOURNAL OF CHEMICAL PHYSICS, 2003, 118 (20) :9208-9215

[5] Single-pulse coherently controlled nonlinear Raman spectroscopy and microscopy [J].

Dudovich, N ;

Oron, D ;

Silberberg, Y .

NATURE, 2002, 418 (6897) :512-514

[6] Coherent Anti-Stokes Raman Scattering Microscopy: Chemical Imaging for Biology and Medicine [J].

Evans, Conor. L. ;

Xie, X. Sunney .

ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, 2008, 1 (01) :883-909

[7] Spectral focusing: High spectral resolution spectroscopy with broad-bandwidth laser pulses [J].

Hellerer, T ;

Enejder, AMK ;

Zumbusch, A .

APPLIED PHYSICS LETTERS, 2004, 85 (01) :25-27

[8] Single-pulse coherent anti-Stokes Raman scattering microscopy employing an octave spanning pulse [J].

Isobe, Keisuke ;

Suda, Akira ;

Tanaka, Masahiro ;

Hashimoto, Hiroshi ;

Kannari, Fumihiko ;

Kawano, Hiroyuki ;

Mizuno, Hideaki ;

Miyawaki, Atsushi ;

Midorikawa, Katsumi .

OPTICS EXPRESS, 2009, 17 (14) :11259-11266

[9] Standoff detection of trace amounts of solids by nonlinear Raman spectroscopy using shaped femtosecond pulses [J].

Katz, O. ;

Natan, A. ;

Silberberg, Y. ;

Rosenwaks, S. .

APPLIED PHYSICS LETTERS, 2008, 92 (17)

[10] Single source coherent anti-Stokes Raman microspectroscopy using spectral focusing [J].

Langbein, Wolfgang ;

Rocha-Mendoza, Israel ;

Borri, Paola .

APPLIED PHYSICS LETTERS, 2009, 95 (08)

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