Is infliximab safe to use while breastfeeding?

被引：71

作者：

Stengel, Joel Z. ^{[1
]}

Arnold, Hays L. ^{[1
]}

机构：

[1] Brooke Army Med Ctr, Gastroenterol Serv, Ft Sam Houston, TX 78234 USA

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2008年 / 14卷 / 19期

关键词：

inflammatory bowel disease; ulcerative colitis; Crohn's disease; pregnancy; breast-feeding; monoclonal antibodies;

D O I：

10.3748/wjg.14.3085

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Inflammatory bowel disease (IBD) often affects women around the age of conception and pregnancy. Most drugs used to treat IBD are safe in pregnancy, but physicians must consider the clinical implications of certain treatment regimens in young, fertile females. We report an informative case of a pregnant patient with IBD who underwent treatment with infliximab during her pregnancy and while nursing her infant. Serum and breast milk infliximab levels were monitored throughout this time period. This case report suggests that targeted monoclonal antibodies and other biologic agents can be used with caution in pregnant and breastfeeding patients. (C) 2008 WJG. All rights reserved.

引用

页码：3085 / 3087

页数：3

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