Genetic diversity of noroviruses in Brazil

被引:43
作者
Fioretti, Julia Monassa [1 ]
Rocha Ferreira, Monica Simoes [1 ]
Victoria, Matias [1 ]
Vieira, Carmen Baur [1 ]
Trindade Pinheiro Xavier, Maria da Penha [1 ]
Gagliardi Leite, Jose Paulo [1 ]
Miagostovich, Marize Pereira [1 ]
机构
[1] Inst Oswaldo Cruz Fiocruz, Lab Virol Comparada & Ambiental, Rio De Janeiro, RJ, Brazil
来源
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2011年 / 106卷 / 08期
关键词
norovirus; genotypes; gastroenteritis; Brazil; ROUND-STRUCTURED VIRUSES; NORWALK-LIKE VIRUSES; REVERSE TRANSCRIPTION PCR; RIO-DE-JANEIRO; ACUTE GASTROENTERITIS; MOLECULAR EPIDEMIOLOGY; UNITED-STATES; SAO-PAULO; OUTBREAKS; CHILDREN;
D O I
10.1590/S0074-02762011000800008
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Norovirus (NoV) infections are a major cause of acute gastroenteritis outbreaks around the world. In Brazil, the surveillance system for acute diarrhoea does not include the diagnosis of NoV, precluding the ability to assess its impact on public health. The present study assessed the circulation of NoV genotypes in different Brazilian states by partial nucleotide sequencing analysis of the genomic region coding for the major capsid viral protein. NoV genogroup II genotype 4 (GII.4) was the prevalent (78%) followed by GII.6, GII.7, GII.12, GII.16 and GII.17, demonstrating the great diversity of NoV genotypes circulating in Brazil. Thus, this paper highlights the importance of a virological surveillance system to detect and characterize emerging strains of NoV and their spreading potential.
引用
收藏
页码:942 / 947
页数:6
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