The complete genomic sequence of an HTLV-II isolate from a Guahibo Indian from Venezuela

被引：11
作者：
Dube, S
Love, JL
Dube, DK
Leon-Ponte, M
de Perez, GE
Baroja, ML
Bianco, N
Poiesz, BJ
机构：
[1] SUNY Hlth Sci Ctr, Dept Med, Syracuse, NY 13210 USA
[2] SUNY Hlth Sci Ctr, Dept Anat & Cell Biol, Syracuse, NY 13210 USA
[3] SUNY Hlth Sci Ctr, Dept Immunol Microbiol, Syracuse, NY 13210 USA
[4] Cent Univ Venezuela, Fac Med, Inst Immunol, Caracas, Venezuela
来源：
VIROLOGY | 1999年 / 253卷 / 02期
关键词：
D O I：
10.1006/viro.1998.9515
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A polyclonal CD3(+), CD8(+) T-cell line, G2, was derived from the peripheral blood of a seropositive, PCR-positive, HTLV-IIB infected Guahibo Indian from Venezuela. The cell line is productively infected with HTLV-IIB. The entire HTLV-II G2 proviral DNA was sequenced via PCR using overlapping HTLV-II primer pairs. Phylogenetic analyses indicate that HTLV-II G2 is the most divergent HTLV-IIB strain identified to date. Characterization of its deduced proteins and its relationship to other members of the PTLV/BLV genus of retroviruses are discussed. (C) 1999 Academic Press.
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页码：181 / 192
页数：12
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