The obstetric antiphospholipid syndrome

被引：36

作者：

Derksen, R. H. W. M. ^{[1
]}

de Grootb, Ph. G. ^{[2
]}

机构：

[1] Univ Med Ctr, Dept Rheumatol & Clin Immunol, Utrecht, Netherlands

[2] Univ Med Ctr, Thrombosis & Haemostasis Lab, Dept Clin Chem & Haematol, Utrecht, Netherlands

来源：

JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 2008年 / 77卷 / 01期

关键词：

antiphospholipid syndrome; lupus anticogulans; anticardiolipin antibodies; recurrent pregnancy loss; fetal loss; RECURRENT PREGNANCY LOSS; LOW-DOSE ASPIRIN; INTERNATIONAL CONSENSUS STATEMENT; GLYCOPROTEIN-I ANTIBODIES; MOLECULAR-WEIGHT HEPARIN; LUPUS ANTICOAGULANT; ANTICARDIOLIPIN ANTIBODIES; FETAL LOSS; CLASSIFICATION CRITERIA; CONTROLLED-TRIAL;

D O I：

10.1016/j.jri.2006.12.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The association of persistent presence of circulating antiphospholipid antibodies and thromboembolic events, (recurrent) pregnancy loss or both is termed antiphospholipid syndrome. Pregnancies in women with the syndrome should be regarded as at high-risk for complications. Optimal management consisting of close follow-up and pharmacological treatment can result in about 70-80% live births. Apart from the laboratory diagnosis of the syndrome and pathophysiology, this review will focus on treatment during pregnancy. (c) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：41 / 50

页数：10

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