Nanostructured lipid carriers: Promising delivery systems for encapsulation of food ingredients

被引:55
|
作者
Azar, Farnaz Ahmadzadeh Nobari [1 ]
Pezeshki, Akram [1 ]
Ghanbarzadeh, Babak [1 ,2 ]
Hamishehkar, Hamed [3 ]
Mohammadi, Maryam [1 ]
机构
[1] Univ Tabriz, Dept Food Sci & Technol, Fac Agr, Tabriz, Iran
[2] Near East Univ, Fac Engn, Dept Food Engn, Mersin 10, Nicosia, Cyprus
[3] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran
关键词
Nanostructured lipid carrier; Encapsulation; Delivery; Stability; NANOPARTICLES SLN; DRUG-DELIVERY; PHYSICOCHEMICAL PROPERTIES; CONTROLLED-RELEASE; CORN-OIL; NLC; FORMULATION; DISSOLUTION; DESIGN; ACID;
D O I
10.1016/j.jafr.2020.100084
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
In the last few decades, various bioactive compound-delivery technologies have been emerged and nanoscale delivery devices have been developed. Nanostructured lipid carriers (NLCs) are delivery systems that reveal some advantages over conventional carriers such as increased loading capacity, encapsulation efficiency, solubility, storage stability, bioavailability, and half-life. Moreover, they provide controlled compound release and safety for food systems. In this review, aspects of NLCs, their components, production methods, bioactive compound incorporation, release, stability, and food applications are introduced.
引用
收藏
页数:8
相关论文
共 50 条
  • [21] Innovating alopecia treatment: nanostructured lipid carriers as advanced delivery platforms
    Kushwaha, Poonam
    Usmani, Shazia
    Sufiyan, Mohd.
    Singh, Priyanka
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2025, : 6391 - 6405
  • [22] Co-encapsulation systems for delivery of bioactive ingredients
    Liu, Kang
    Chen, Ying-Ying
    Pan, Li-Hua
    Li, Qiang-Ming
    Luo, Jian-Ping
    Zha, Xue-Qiang
    FOOD RESEARCH INTERNATIONAL, 2022, 155
  • [23] Preparation and Characterization of Vitamin A Palmitate-loaded Nanostructured Lipid Carriers as Delivery Systems for food products
    Kong, Rong
    Xia, Qiang
    Liu, Guangyu
    APPLICATION OF CHEMICAL ENGINEERING, PTS 1-3, 2011, 236-238 : 1818 - 1823
  • [24] Encapsulation of Food Components and Bioactive Ingredients and Targeted Release
    Alemzadeh, I
    Hajiabbas, M.
    Pakzad, H.
    Dehkordi, S. Sajadi
    Vossoughi, A.
    INTERNATIONAL JOURNAL OF ENGINEERING, 2020, 33 (01): : 1 - 11
  • [25] Enhancing supersaturation maintenance of hydrophobic ingredients using nanostructured lipid carriers: The role of solid lipid type and level
    Song, Zengliu
    Tian, Wenni
    Wang, Chujing
    You, Yang
    Li, Yunqi
    Xiao, Jie
    FOOD CHEMISTRY, 2025, 465
  • [26] Development of nanostructured lipid carriers as a promising tool for methotrexate delivery: physicochemical and in vitro evaluation
    Rathee, Jyoti
    Kanwar, Rohini
    Kumari, Laxmi
    Pawar, Sandip, V
    Sharma, Shikha
    Ali, Md Ehesan
    Salunke, Deepak B.
    Mehta, Surinder Kumar
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (07) : 2747 - 2758
  • [27] Development of nanostructured lipid carriers for intraoral delivery of Domperidone
    Tetyczka, Carolin
    Griesbacher, Martin
    Absenger-Novak, Markus
    Froehlich, Eleonore
    Roblegg, Eva
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 526 (1-2) : 188 - 198
  • [28] Design, development, and preclinical evaluation of pirfenidone-loaded nanostructured lipid carriers for pulmonary delivery
    Chettupalli, Ananda Kumar
    Kakkerla, Anitha
    Jadi, Rajendra Kumar
    Uppu, Pavani
    Ghazwani, Mohammed
    Hani, Umme
    Amarachinta, Padmanabha Rao
    Sarvani, Peri
    Haque, M. Akiful
    SCIENTIFIC REPORTS, 2025, 15 (01):
  • [29] Optimization, stabilization, and characterization of amphotericin B loaded nanostructured lipid carriers for ocular drug delivery
    Lakhani, Prit
    Patil, Akash
    Wu, Kai-Wei
    Sweeney, Corinne
    Tripathi, Siddharth
    Avula, Bharathi
    Taskar, Pranjal
    Khan, Shabana
    Majumdar, Soumyajit
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2019, 572
  • [30] Nanostructured lipid carriers based nanogel for meloxicam delivery: mechanistic, in-vivo and stability evaluation
    Khurana, S.
    Jain, N. K.
    Bedi, P. M. S.
    DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2015, 41 (08) : 1368 - 1375