On-chip measurement of the Brownian relaxation frequency of magnetic beads using magnetic tunneling junctions

被引：19

作者：

Donolato, M. ^{[1
]}

Sogne, E. ^{[1
]}

Dalslet, B. T. ^{[2
]}

Cantoni, M. ^{[1
]}

Petti, D. ^{[1
]}

Cao, J. ^{[3
]}

Cardoso, F. ^{[3
]}

Cardoso, S. ^{[3
]}

Freitas, P. P. ^{[3
]}

Hansen, M. F. ^{[2
]}

Bertacco, R. ^{[1
]}

机构：

[1] Politecn Milan, L NESS, Dipartimento Fis, I-22100 Como, Italy

[2] Tech Univ Denmark, DTU Nanotech, Dept Micro & Nanotechnol, DK-2800 Lyngby, Denmark

[3] INESC Microsistemas & Nanotecnol INESC MN, P-1000029 Lisbon, Portugal

来源：

APPLIED PHYSICS LETTERS | 2011年 / 98卷 / 07期

关键词：

BIOSENSORS;

D O I：

10.1063/1.3554374

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We demonstrate the detection of the Brownian relaxation frequency of 250 nm diameter magnetic beads using a lab-on-chip platform based on current lines for exciting the beads with alternating magnetic fields and highly sensitive magnetic tunnel junction (MTJ) sensors with a superparamagnetic free layer. The first harmonic out-of-phase component of the MTJ response gives the imaginary part of the magnetic bead susceptibility, which peaks at the Brownian relaxation frequency. This work paves the way to on-chip implementation of Brownian magnetorelaxometry in innovative "lab-on-a-bead" assays for biomolecular recognition. (C) 2011 American Institute of Physics. [doi:10.1063/1.3554374]

引用

页数：3

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