Risk of colorectal cancer in patients with positive results of fecal immunochemical test performed within 5 years since the last colonoscopy

被引:5
作者
Jung, Yoon Suk [1 ]
Lee, Jinhee [2 ]
Moon, Chang Mo [3 ,4 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Dept Internal Med, Div Gastroenterol, Seoul, South Korea
[2] Ajou Univ, Dept Endocrinol & Metab, Sch Med, Suwon, South Korea
[3] Ewha Womans Univ, Coll Med, Dept Internal Med, 1071 Anyangcheon Ro, Seoul 07985, South Korea
[4] Ewha Womans Univ, Coll Med, Inflammat Canc Microenvironm Res Ctr, Seoul, South Korea
关键词
Fecal immunochemical test; Colorectal neoplasms; Colonoscopy; SOCIETY-TASK-FORCE; OCCULT-BLOOD; AVERAGE-RISK; RECOMMENDATIONS; SURVEILLANCE; POLYPECTOMY; PHYSICIANS;
D O I
10.3904/kjim.2020.525
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background/Aims: Annual fecal immunochemical tests (FITs) are often repeated within the recommended colonoscopy surveillance intervals. However, it remains unclear whether interval FITs are useful. To answer this question, we assessed the risk of colorectal cancer (CRC) according to the interval from the last colonoscopy to an FIT. Methods: Using the Korean National Cancer Screening Program database, we collected data on patients who underwent FITs in 2011. Patients with positive FIT results were classified into three groups according to their previous colonoscopy interval: 0.5 to 5 years (group 1), 5 to 10 years (group 2), and >= 10 years or no colonoscopy (group 3). CRC incidence was defined as CRC diagnosed within 1 year after an FIT. Results: Among 177,660 patients with positive FIT results, the incidence of CRC in groups 1, 2, and 3 was 0.72% (n = 214/29,575), 1.28% (n = 116/9,083), and 3.88% (n = 5,387/139,002), respectively. The age-and sex-adjusted risk for CRC was higher in groups 2 (odds ratio [OR], 1.79; 95% confidence interval [CI], 1.43 to 2.25) and 3 (OR, 5.56; 95% CI, 4.85 to 6.38) than in group 1. Among patients who did and did not undergo a polypectomy during the previous colonoscopy, those in group 2 had a higher rate of CRC than those in group 1 (without polypectomy: 1.15% vs. 0.63%; OR, 1.79; 95% CI, 1.37 to 2.34) (with polypectomy: 2.37% vs. 0.93 %; OR, 2.30; 95% CI, 1.44 to 3.69). Conclusion: In patients with positive FIT results who had undergone a colonoscopy within the past 5 years, the risk of CRC is very low, regardless of whether a polypectomy was performed, suggesting that interval FITs are not useful.
引用
收藏
页码:1083 / 1091
页数:9
相关论文
共 19 条
[1]  
BARROWS GH, 1978, AM J CLIN PATHOL, V69, P342
[2]   Randomised controlled trial of faecal-occult-blood screening for colorectal cancer [J].
Hardcastle, JD ;
Chamberlain, JO ;
Robinson, MHE ;
Moss, SM ;
Amar, SS ;
Balfour, TW ;
James, PD ;
Mangham, CM .
LANCET, 1996, 348 (9040) :1472-1477
[3]   Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020 [J].
Hassan, Cesare ;
Antonelli, Giulio ;
Dumonceau, Jean-Marc ;
Regula, Jaroslaw ;
Bretthauer, Michael ;
Chaussade, Stanislas ;
Dekker, Evelien ;
Ferlitsch, Monika ;
Gimeno-Garcia, Antonio ;
Jover, Rodrigo ;
Kalager, Mette ;
Pellise, Maria ;
Pox, Christian ;
Ricciardiello, Luigi ;
Rutter, Matthew ;
Helsingen, Lise Morkved ;
Bleijenberg, Arne ;
Senore, Carlo ;
van Hooft, Jeanin E. ;
Dinis-Ribeiro, Mario ;
Quintero, Enrique .
ENDOSCOPY, 2020, 52 (08) :687-700
[4]   Risk of colorectal cancer for fecal immunochemistry test-positive, average-risk patients after a colonoscopy [J].
Kawamura, Takuji ;
Nakamura, Shiho ;
Sone, Daiki ;
Sakai, Hiroaki ;
Amamiya, Kana ;
Inoue, Naonori ;
Sakiyama, Naokuni ;
Shirakawa, Atsushi ;
Okada, Yusuke ;
Sanada, Kasumi ;
Nakase, Kojiro ;
Mandai, Koichiro ;
Suzuki, Azumi ;
Morita, Atsuhiro ;
Tanaka, Kiyohito ;
Uno, Koji ;
Yasuda, Kenjiro .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2019, 34 (03) :532-536
[5]   Yield of repeat colonoscopy in asymptomatic individuals with a positive fecal immunochemical test and recent colonoscopy [J].
Kim, Nam Hee ;
Jung, Yoon Suk ;
Lim, Jae Wan ;
Park, Jung Ho ;
Park, Dong Il ;
Sohn, Chong Il .
GASTROINTESTINAL ENDOSCOPY, 2019, 89 (05) :1037-1043
[6]   Randomised study of screening for colorectal cancer with faecal-occult-blood test [J].
Kronborg, O ;
Fenger, C ;
Olsen, J ;
Jorgensen, OD ;
Sondergaard, O .
LANCET, 1996, 348 (9040) :1467-1471
[7]   Standardized colonoscopy reporting and data system: report of the Quality Assurance Task Group of the National Colorectal Cancer Roundtable [J].
Lieberman, David ;
Nadel, Marion ;
Smith, Robert A. ;
Atkin, Wendy ;
Duggirala, Subash B. ;
Fletcher, Robert ;
Glick, Seth N. ;
Johnson, C. Daniel ;
Levin, Theodore R. ;
Pope, John B. ;
Potter, Michael B. ;
Ransohoff, David ;
Rex, Douglas ;
Schoen, Robert ;
Schroy, Paul ;
Winawer, Sidney .
GASTROINTESTINAL ENDOSCOPY, 2007, 65 (06) :757-766
[8]   Annual Fecal Occult Blood Testing can be Safely Suspended for up to 5 Years After a Negative Colonoscopy in Asymptomatic Average-Risk Patients [J].
Liu, Jennifer ;
Finkelstein, Steven ;
Francois, Fritz .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2015, 110 (09) :1355-1358
[9]  
MACRAE FA, 1982, GASTROENTEROLOGY, V82, P899
[10]   Fecal Occult Blood Testing Beliefs and Practices of US Primary Care Physicians: Serious Deviations from Evidence-Based Recommendations [J].
Nadel, Marion R. ;
Berkowitz, Zahava ;
Klabunde, Carrie N. ;
Smith, Robert A. ;
Coughlin, Steven S. ;
White, Mary C. .
JOURNAL OF GENERAL INTERNAL MEDICINE, 2010, 25 (08) :833-839