In vitro degradation behavior of Mg scaffolds with three-dimensional interconnected porous structures for bone tissue engineering

被引：42
作者：
Jia, Gaozhi [1 ,2 ]
Chen, Chenxin [1 ,2 ]
Zhang, Jian [1 ,2 ]
Wang, Yinchuan [1 ,2 ]
Yue, Rui [1 ,2 ]
Luthringer-Feyerabend, Berengere J. C. [4 ]
Willumeit-Roemer, Regine [4 ]
Zhang, Hua [1 ,2 ]
Xiong, Meiping [3 ]
Huang, Hua [1 ,2 ]
Yuan, Guangyin [1 ,2 ]
Feyerabend, Frank [4 ]
机构：
[1] Shanghai Jiao Tong Univ, Sch Mat Sci & Engn, Natl Engn Res Ctr Light Alloy Net Forming, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, State Key Lab Met Matrix Composite, Sch Mat Sci & Engn, Shanghai 200240, Peoples R China
[3] Fudan Univ, Peoples Hosp Shanghai 5, Dept Stomatol, Shanghai 200240, Peoples R China
[4] Helmholtz Zentrum Geesthacht, Div Metall Biomat, Inst Mat Res, Max Planck Str 1, D-21502 Geesthacht, Germany
来源：
CORROSION SCIENCE | 2018年 / 144卷
基金：
中国国家自然科学基金;
关键词：
Magnesium scaffolds; Three-dimensional; Interconnectivity; Pore strut; Degradation behavior; ZN-ZR ALLOY; DYNAMIC DEGRADATION; SIMULATED ENVIRONMENT; CORROSION-RESISTANCE; MAGNESIUM SCAFFOLD; IMPLANT INTERFACE; VIVO; DESIGN; OSSEOINTEGRATION; BIOCOMPATIBILITY;
D O I：
10.1016/j.corsci.2018.09.001
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
The degradation behavior in consideration of the pore strut and the interconnectivity of two Mg scaffolds with different three-dimensional interconnected porous structures were evaluated. The interconnectivity of the two scaffolds gradually decreased along with the clogged interconnected pores due to the deposition formation on the pore wall. Mg scaffold with spherical pores and cambered pore strut degraded faster but exhibited better resistance to the deterioration of the interconnectivity compared with Mg scaffold with irregular pores and polygonal pore struts. Direct cell culture of MC3T3-E1 osteoblasts on the two scaffolds indicated a promising potential for bone tissue engineering.
引用
收藏
页码：301 / 312
页数：12
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