Adherence to Surgical Antibiotic Prophylaxis in the Field of Vascular Surgery

被引：1

作者：

Temme, Pjotr ^{[1
]}

Nagtegaal, Elsbeth ^{[2
]}

Jong, Eefje ^{[3
]}

Buijtels, Patricia ^{[4
]}

de Wilde, Sofieke ^{[2
]}

机构：

[1] Univ Utrecht, Dept Pharmaceut Sci, Utrecht, Netherlands

[2] Meander Med Ctr, Dept Hosp Pharm, Amersfoort, Netherlands

[3] Meander Med Ctr, Dept Internal Med, Amersfoort, Netherlands

[4] Meander Med Ctr, Dept Clin Microbiol, Amersfoort, Netherlands

来源：

SURGICAL INFECTIONS | 2022年 / 23卷 / 02期

关键词：

antibiotic prophylaxis; antibiotic stewardship; guideline adherence; surgical site infection; vascular surgery; ANTIMICROBIAL PROPHYLAXIS; SITE INFECTION; GUIDELINES;

D O I：

10.1089/sur.2021.254

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background: Insufficient surgical antibiotic prophylaxis (SAP) can lead to prolonged hospitalization, hospital re-admissions, increased morbidity and mortality, and higher healthcare costs. Overdoing prophylaxis can result in antimicrobial resistance, Clostridium difficile infections, and acute kidney failure. Patients and Methods: To investigate the adherence to local SAP guidelines for vascular surgery, a retrospective observational single center intervention study was performed in a Dutch hospital. Results: Antibiotic choice, dose, interval, timing, and duration were adherent to the guidelines in 96%, 97%, 96%, 85%, and 41% of the surgeries, respectively. Adherence to all five aspects was achieved in only 37% of all procedures. Conclusions: Further interventions are necessary to improve specific parameters such as duration and timing.

引用

页码：155 / 158

页数：4

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