Current strategies for knee cartilage repair

被引：62
作者：
Kalson, N. S. [1 ]
Gikas, P. D. [1 ]
Briggs, T. W. R. [1 ]
机构：
[1] Royal Natl Orthopaed Hosp, Bone Tumour Serv, Stanmore HA7 4LP, Middx, England
来源：
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE | 2010年 / 64卷 / 10期
关键词：
AUTOLOGOUS CHONDROCYTE IMPLANTATION; ARTICULAR-CARTILAGE; MICROFRACTURE TECHNIQUE; CHONDRAL DEFECTS; OSTEOCHONDRITIS-DISSECANS; RANDOMIZED-TRIAL; LESIONS; TRANSPLANTATION; MOSAICPLASTY; INJURIES;
D O I：
10.1111/j.1742-1241.2010.02420.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
P>Defects in knee articular cartilage (AC) can cause pain and disability and present the clinician with an extremely challenging clinical situation. This article describes the most up-to-date surgical techniques that aim to repair and/or regenerate symptomatic focal defects in AC, which include arthroscopic debridement, microfracture bone marrow stimulation and autologous osteochondral allografting, with an emphasis on autologous chondrocyte implantation. In the future, refinement of tissue-engineering approaches promises to further improve outcome for these patients.
引用
收藏
页码：1444 / 1452
页数：9
相关论文
共 71 条
[31]   A prospective, randomised comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee [J].
Kish, G ;
Hangody, L .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2004, 86B (04) :619-619
[32]   Autologous chondrocyte implantation compared with microfracture in the knee - A randomized trial [J].
Knutsen, G ;
Engebretsen, L ;
Ludvigsen, TC ;
Drogset, JO ;
Grontvedt, T ;
Solheim, E ;
Strand, T ;
Roberts, S ;
Isaksen, V ;
Johansen, C .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2004, 86A (03) :455-464
[33]   A Randomized trial comparing autologous chondrocyte implantation with microfracture [J].
Knutsen, Gunnar ;
Drogset, Jon Olav ;
Engebretsen, Lars ;
Grontvedt, Torbjorn ;
Isaksen, Vidar ;
Ludvigsen, Tom C. ;
Roberts, Sally ;
Solheim, Eirik ;
Strand, Torbjorn ;
Johansen, Oddmund .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2007, 89A (10) :2105-2112
[34]   Second Generation Issues in Cartilage Repair [J].
Kon, Elizaveta ;
Delcogliano, Marco ;
Filardo, Giuseppe ;
Montaperto, Clara ;
Marcacci, Maurilio .
SPORTS MEDICINE AND ARTHROSCOPY REVIEW, 2008, 16 (04) :221-229
[35]   Arthroscopic Second-Generation Autologous Chondrocyte Implantation Compared With Microfracture for Chondral Lesions of the Knee Prospective Nonrandomized Study at 5 Years [J].
Kon, Elizaveta ;
Gobbi, Alberto ;
Filardo, Giuseppe ;
Delcogliano, Marco ;
Zaffagnini, Stefano ;
Marcacci, Maurilio .
AMERICAN JOURNAL OF SPORTS MEDICINE, 2009, 37 (01) :33-41
[36]   Results after microfracture of full-thickness chondral defects in different compartments in the knee [J].
Kreuz, P. C. ;
Steinwachs, M. R. ;
Erggelet, C. ;
Krause, S. J. ;
Konrad, G. ;
Uhl, M. ;
Suedkamp, N. .
OSTEOARTHRITIS AND CARTILAGE, 2006, 14 (11) :1119-1125
[37]   Microfracture of chondral defects in the knee associated with different results in patients aged 40 years or younger? [J].
Kreuz, Peter C. ;
Erggelet, Christoph ;
Steinwachs, Matthias R. ;
Krause, Stefanie J. ;
Lahm, Andreas ;
Niemeyer, Philipp ;
Ghanem, Nadir ;
Uhl, Markus ;
Suedkamp, Norbert .
ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY, 2006, 22 (11) :1180-1186
[38]   Chondral delamination of the knee in soccer players [J].
Levy, AS ;
Lohnes, J ;
Sculley, S ;
LeCroy, M ;
Garrett, W .
AMERICAN JOURNAL OF SPORTS MEDICINE, 1996, 24 (05) :634-639
[39]   Surgical options for patients with osteoarthritis of the knee [J].
Luetzner, Joerg ;
Kasten, Philip ;
Guenther, Klaus-Peter ;
Kirschner, Stephan .
NATURE REVIEWS RHEUMATOLOGY, 2009, 5 (06) :309-316
[40]   Treatment of focal articular cartilage defects in the knee [J].
Magnussen, Robert A. ;
Dunn, Warren R. ;
Carey, James L. ;
Spindler, Kurt P. .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2008, 466 (04) :952-962
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