Rapid and Dramatic Radiographic and Clinical Response to an ALK Inhibitor (Crizotinib, PF02341066) in an ALK Translocation-Positive Patient with Non-small Cell Lung Cancer

被引：69

作者：

Ou, Sai-Hong Ignatius ^{[1
]}

Bazhenova, Lyudmila ^{[2
]}

Camidge, D. Ross ^{[3
]}

Solomon, Benjamin J. ^{[4
]}

Herman, June ^{[5
]}

Kain, Tatiana ^{[5
]}

Bang, Yung-Jue ^{[6
]}

Kwak, Eunice L. ^{[7
]}

Shaw, Alice T. ^{[7
]}

Salgia, Ravi ^{[8
]}

Maki, Robert G. ^{[9
]}

Clark, Jeffrey W. ^{[7
]}

Wilner, Keith D. ^{[10
]}

Iafrate, A. John ^{[7
,11
]}

机构：

[1] Univ Calif Irvine, Div Hematol Oncol, Dept Med, Chao Family Comprehens Canc Ctr,Med Ctr, Orange, CA 92868 USA

[2] Univ Calif San Diego, Med Ctr, Moores Canc Ctr, La Jolla, CA 92093 USA

[3] Univ Colorado, Ctr Canc, Aurora, CO USA

[4] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia

[5] Univ Calif Irvine, Div Mol Imaging, Dept Radiol Sci, Chao Family Comprehens Canc Ctr,Med Ctr, Orange, CA 92868 USA

[6] Seoul Natl Univ Hosp, Dept Internal Med, Seoul 110744, South Korea

[7] Massachusetts Gen Hosp, Ctr Canc, Boston, MA USA

[8] Univ Chicago, Med Ctr, Chicago, IL 60637 USA

[9] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[10] Pfizer Global Res & Dev, Dept Clin Res, La Jolla, CA USA

[11] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA

来源：

JOURNAL OF THORACIC ONCOLOGY | 2010年 / 5卷 / 12期

关键词：

18-FDG PET/CT; Adenocarcinoma of the lung; ALK positive NSCLC; Crizotinib (PF02341066); ALK FISH testing; Anaplastic lymphoma kinase; EML4-ALK;

D O I：

10.1097/JTO.0b013e318200f9ff

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：2044 / 2046

页数：3

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