APECED: a monogenic autoimmune disease providing new clues to self-tolerance

被引：74

作者：

Peterson, P ^{[1
]}

Nagamine, K

Scott, H

Heino, M

Kudoh, J

Shimizu, N

Antonarakis, SE

Krohn, KJE

机构：

[1] Univ Tampere, Inst Med Technol, SF-33101 Tampere, Finland

[2] Univ Tampere, Univ Hosp, SF-33101 Tampere, Finland

[3] Keio Univ, Sch Med, Dept Mol Biol, Shinjuku Ku, Tokyo 160, Japan

[4] Univ Geneva, Sch Med, Dept Genet & Microbiol, Lab Human Mol Genet, Geneva 4, Switzerland

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 09期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/S0167-5699(98)01293-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The cloning of AIRE, the gene for autoimmune polyendocrinopathy-candidiais-ectodermal dystrophy (APECED) promises to unravel some of the mysteries of autoimmunity. Here, Part Peterson and colleagues discuss recent studies of AIRE and the implications for disease therapy.

引用

页码：384 / 386

页数：3

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